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Acute appendicitis – a study with special reference to diagnostics, severity assessment and association with appendiceal neoplasms
Turun yliopiston julkaisuja. Sarja D: Medica, Odontologica : 1411 (01.03.2019)Acute appendicitis is the most common indication for emergency abdominal surgery. Today, it is generally accepted that acute appendicitis does not invariably progress to perforation. Recent studies have shown that the ... -
Adverse effects of Bacillus Calmette-Guérin (BCG) therapy in the treatment of non-muscle-invasive bladder cancer
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1735 (Turun yliopisto, 22.09.2023)Bacillus Calmette-Guérin (BCG) is the standard treatment option for non-muscleinvasive bladder cancer (NMIBC). The mechanism of BCG relies on live mycobacteria inducing an immune response in the bladder wall and is therefore ... -
Assessment of disease activity of inflammatory bowel disease using positron emission tomography / magnetic resonance imaging and keratin 7 -analysis
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1772 (Turun yliopisto, 08.03.2024)The clinical course of inflammatory bowel disease (IBD) is characterized by relapses and spontaneous or drug-induced remissions, but it cannot be predicted by currently known parameters. The priority of this thesis was to ... -
Challenges in diagnostics of Prostate cancer
(Turun yliopisto, 29.05.2020)Prostate cancer (PCa) is the most frequently diagnosed cancer in men and it is one of the leading causes of men’s cancer deaths in the developed countries. It can be considered as a continuum of neoplasms with aggressiveness ... -
Clinical and molecular manifestations of lower limb peripheral artery disease
Turun yliopiston julkaisuja. Sarja D: Medica, Odontologica : 1311 (Turun yliopisto, 10.11.2017)Lower limb peripheral artery disease (PAD) is poorly known by the general public and even health care professionals. The manifestations of PAD are diverse depending on the prevailing cardiovascular risk factors leading to ... -
Clinical efficacy of platelet-rich plasma injections in common musculoskeletal disorders
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 777 (Turun yliopisto, 08.03.2024)Together osteoarthritis (OA) of the knee, epicondylitis of the elbow and tendinopathy of the shoulder rotator cuff (RC) affect 5.9% to 13.8% of the general population worldwide. These conditions cause significant disability ... -
Congenital abdominal wall defects in Finland 1993-2014 : Epidemiology and risk factors
Turun yliopiston julkaisua -Annales Universitatis Turkuensis, Ser. D: Medica-Odongologica : 1496 (Turun yliopisto, 21.08.2020)Congenital abdominal wall defects are a group of malformations among which gastroschisis and omphalocele are the most common. In omphalocele, abdominal organs are herniated through an open umbilical ring and the defect is ... -
Diagnosis and treatment of obstetric anal sphincter injuries
Turun yliopiston julkaisuja. Sarja D: Medica, Odontologica : 1425 (Turun yliopisto, 13.09.2019)Aims: The aims of this study were to identify the risk factors for a failed primary repair of obstetric anal sphincter injury (OASI), to determine whether external phased-array magnetic resonance imaging (MRI) is suitable ... -
INSIGHT ON THYMOSIN BETA 4 IN ANIMAL MODELS OF MYOCARDIAL INJURY
Turun yliopiston julkaisuja. Sarja D, Medica - Odontologica : 1303 (Turun yliopisto, 27.10.2017)The use of small and large animal models is vital in the clinical translation of experimental data in cardiovascular research. Thymosin beta 4 is a peptide which has shown good cardioprotective potential in several in vitro ... -
Invasive treatment of lower extremity arterial disease – National procedure rates and challenges in wound healing
Turun yliopiston julkaisua -Annales Universitatis Turkuensis, Ser. D: Medica-Odongologica : 1528 (Turun yliopisto, 15.01.2021)Globally, over 200 million people suffer from lower extremity arterial disease (LEAD). The population is aging and with it the prevalence of LEAD is increasing especially in developing countries. The number of revascularization ... -
Long-term outcomes of laparoscopic sleeve gastrectomy vs. laparoscopic Roux-en-Y gastric bypass: Special focus on procedure selection, gastroesophageal reflux, and quality of life
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1755 (Turun yliopisto, 01.12.2023)Background: Severe obesity is an increasing global epidemic. To date, metabolic bariatric surgery (MBS) is the only treatment for severe obesity with good and sustainable long-term weight loss and remission of obesity ... -
Melanoma in children, adolescents and young adults
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1631 (Turun yliopisto, 03.06.2022)BACKGROUND: Cutaneous melanoma in children and adolescents is a rare malignancy, and specific treatment guidelines have not been established for this patient group. Also, Spitzoid tumours in the young pose diagnostic ... -
Metabolism, Morphology, and Effect of Fat Grafts - Studies on Fat Graft Browning and Therapeutic Use in the Prevention of Peritoneal Adhesions
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1771 (Turun yliopisto, 09.02.2024)BACKGROUND: Fat transfer is a basic technique in the field of plastic surgery, but so far, there is very little information about what happens to fat grafts after transfer. The aim of this dissertation was to determine ... -
Neoadjuvant chemotherapy in muscle-invasive bladder cancer
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1485 (Turun yliopisto, 28.08.2020)Bladder cancer can be divided into non-muscle-invasive and muscle-invasive types. In the muscle-invasive type of bladder cancer, removal of the bladder and internal genitalia is the cornerstone of treatment. Treatment ... -
Novel imaging and image-guided therapy of prostate cancer
Turun yliopiston julkaisua -Annales Universitatis Turkuensis, Ser. D: Medica-Odongologica : 1555 (Turun yliopisto, 27.08.2021)Whole-gland prostate surgery and radiotherapy, the established approaches to localised prostate cancer (PCa), usually cause substantial adverse effects. Targeted image-guided cancer therapy has gained acceptance through ... -
Outcomes after ascending aortic surgery : registry-based studies with special emphasis on reoperations and pre-operative cardiac arrest
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1439 (Turun yliopisto, 23.08.2019)Surgical repair for ascending aorta regarding an aneurysm or an acute type A aortic dissection (ATAAD) share similar principals in techniques. ATAAD is highly lethal, and the appropriate extent of surgery at acute setting ... -
Pressure Measurements, Lesion Distribution and Outcome in Peripheral Artery Disease
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1732 (Turun yliopisto, 15.09.2023)Peripheral artery disease (PAD) causes increased all-cause and cardiovascular (CV) mortality. These increases have been associated with abnormal ankle-brachial indices and the extent of atherosclerotic lesions as measured ... -
Rectal cancer surgery – opportunities and challenges in the modern era
Turun yliopiston julkaisua -Annales Universitatis Turkuensis, Ser. D: Medica-Odongologica : 1526 (Turun yliopisto, 29.01.2021)Aims: This thesis was designed to elucidate the opportunities and challenges faced by the surgeon and the patient in the era of modern rectal cancer surgery. Temporal changes in the treatment and survival of patients with ... -
Studies on prostate-specific antigen and prostate cancer epidemiology
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1321 (15.12.2017)The prostate-specific antigen (PSA) is the main biomarker for diagnosis and treatment response monitoring in prostate cancer (PCa). In the first part of this thesis, we investigated the prognostic value of ultrasensitive ... -
The WHO surgical safety checklist in neurosurgery
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1448 (Turun yliopisto, 13.12.2019)The World Health Organization’s surgical safety checklist (WHO SSC) is designed to improve adherence to operating room safety standards. Its use has been shown to reduce surgical morbidity and mortality. Studies on solely ...
