Hae
Aineistot 1321-1330 / 2117
Transcriptional Profiling of Organ‐Specific Autoimmunity in Human
(Annales Universitatis Turkuensis D 983Turun yliopisto, 2011-11-04)
Our understanding of the pathogenesis of organ‐specific autoinflammation has been restricted by limited access to the target organs. Peripheral blood, however, as a preferred transportation route for immune cells, provides ...
The effects of selective estrogen receptor modulators on the death of breast cancer cells and osteoblastic cells
(Turun yliopisto, 2008-04-04)
<b>Selektiivisten estrogeenireseptorin muuntelijoiden (serm) vaikutus rintasyöpäsolujen ja luun solujen kuolemaan</b>
Selektiiviset estrogeenireseptorin muuntelijat (SERMit) ovat ryhmä kemialliselta rakenteeltaan erilaisia ...
Bridging academic and working life expertise in continuing professional education : A social network perspective
(Turun yliopisto, 2016-11-11)
This dissertation examined efforts to bridge academic and working life expertise in continuing professional education in response to the new requirements of changing world and working life contexts. Its specific aims were ...
Regulation of B Cell Gene Expression and Function by Ikaros, Helios and Bcl6
(Annales Universitatis Turkuensis D 935Turun yliopisto, 2010-12-17)
B lymphocytes constitute a key branch of adaptive immunity by providing specificity to recognize a vast variety of antigens by B cell antigen receptors (BCR) and secreted antibodies. Antigen recognition activates the cells ...
Effects of obesity and resistance exercise on bone health studied with modern imaging methods
(Turun yliopisto, 2017-05-13)
Altered metabolic states, such as obesity and resistance exercise, may affect bone health either in a negative or positive manner. In clinical practice, bone health may be easily understood as a synonym for bone mineral ...
Functional characterization of proteins required for mitotic progression and the spindle assembly checkpoint
(Annales Universitatis Turkuensis D 933Turun yliopisto, 2010-12-03)
During mitotic cell division, the genetic material packed into chromosomes is divided equally between two daughter cells. Before the separation of the two copies of a chromosome (sister chromatids), each chromosome has to ...
The Role of Cytochrome P450 3A Inducers and Inhibitors in the Metabolism and the Effects of Oxycodone
(Annales Universitatis Turkuensis D 932Turun yliopisto, 2010-12-04)
Oxycodone is an opioid used in the treatment of moderate or severe pain. It is principally metabolized in the liver by cytochrome P450 3A (CYP3A) enzymes whereas approximately 10% is metabolized by CYP2D6. Little is known ...
Cardiac Imaging in the Diagnosis of Coronary Artery Disease: The Value of Quantitative Imaging of Myocardial Perfusion and Deformation
(Annales Universitatis Turkuensis D 1216Turun yliopisto, 2016-02-13)
Atherosclerosis is a chronic and progressive disease of the vasculature. Increasing coronary atherosclerosis can lead to obstructive coronary artery disease (CAD) or myocardial infarction. Computed tomography angiography ...
Kaatumisvaaraa lisäävät lääkkeet; Porissa toteutettu iäkkäiden monitekijäinen kaatumisten ehkäisy
(Turun yliopisto, 2011-11-04)
Kaatumiset ovat ikääntyvien yleisimpiä tapaturmia. Niiden seuraukset voivat olla vakavia. Yksilöllisesti toteutetut ehkäisyohjelmat ovat vähentäneet kaatumisvaarassa olevien iäkkäiden kaatumisia. Psyykenlääkkeiden on ...
Targeting Adenoviral Gene Therapy Vectors to Head and Neck Squamous Cell Carcinoma and Heart
(Annales Universitatis Turkuensis D 937Turun yliopisto, 2010-12-03)
Gene therapy aims to treat diseases by introducing genetic material to the diseased tissue. For cancer treatment it is important to destroy cancerous cells; this can be achieved by introducing a gene, which induces cell ...