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Clever-1 in cancer – Assessing the efficacy of a novel immunotherapy approach in patient derived explant cultures
(2020-02-07)
The efficacy of oncological treatments has developed significantly in the past few decades but yet various types of cancer still lack curative treatment. In cancer immunotherapies the object is to guide one’s own immune ...
HLA-DQB1-GEENIN METYLAATIOTASOT LYMFOSYYTEISSÄ TYYPIN 1 DIABETEKSESSA
(2020-05-04)
Tyypin 1 diabetes (T1D) on haiman saarekesoluihin kohdistuvan autoimmuunireaktion pohjalta syntyvä parantumaton pitkäaikaissairaus, jonka ilmaantuvuus ja esiintyvyys ovat kasvaneet maailmanlaajuisesti viime vuosikymmeninä. ...
The role of Robo4 molecule in leukocyte traffic
(2020-12-11)
Leukocyte traffic is an essential part of the immune system as lymphocytes continuously migrate to lymph nodes in search of foreign antigens. Lymphocytes can access the lymph node either via blood vasculature or afferent ...
FETAL –DERIVED MACROPHAGES PERSIST AND SEQUENTIALLY MATURATE IN OVARIES AFTER BIRTH IN MICE
(2020-12-22)
Macrophages and monocytes are a diverse group of white blood cells, which hold a critical role in the immune system but also carry out important functions in tissue development, homeostasis and inflammation. Thus far the ...
Current treatments for non-small cell lung carcinoma
(2021-03-26)
This literature review addresses the subject of non-small-cell lung carcinoma (NSCLC) and the
current treatments for it. For therapeutic purposes, lung carcinomas are histologically grossly
organized into two main ...
Exotoxin targeted drug modalities
(2021-03-31)
According to World Health Organization (WHO), antimicrobial resistance is one of the major global health issues to track in 2021. As the efficiency of current antibiotics have gradually been declining for several decades ...
CD73 as a prognostic biomarker in human pancreatic cancer
(2021-02-01)
Cell surface protein CD73 has important role in sustaining immune homeostasis as the key regulator of extracellular adenosine which mediates immunosuppression and angiogenesis. This CD73 regulated pathway is shown to promote ...
Lymph-derived soluble Clever-1 : Effect on cancer cell viability
(2023-03-02)
Cancer is one of the most important causes of premature death. Even though the treatment of cancer has seen considerable advancements in the past decades, there are still numerous cancers without effective treatment. ...