Selaus laitoksen mukaan kokoelmassa Pro gradu -tutkielmat ja diplomityöt sekä syventävien opintojen opinnäytetyöt (rajattu näkyvyys) Biokemian laitos
Aineistot 21-40 / 85
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Droplet digital PCR for detection of mutations in high-grade serous ovarian cancer
(22.04.2020)Ovarian cancer (OC) is one of the most fatal cancers that affect female reproductive system. It is frequently discovered at advanced stage therefore, the 5-year survival rate is typically low. High grade serous ovarian ...suljettu -
Early diagnosis of breast cancer : detection of altered glycosylation in human haptoglobin
(10.11.2020)Breast cancer (BrCa) is the most common cancer in women worldwide, with 2.1 million of new cases occurring yearly, and the fifth most common cause of death in women. The five-year survival rate for early diagnosed BrCa is ...suljettu -
Effect of Fish Species and Fermentation on Immunological Properties of Allergens from Freshwater Fish
(14.06.2020)With increased freshwater fish consumption in China, hypersensitivity reactions of consumers have become more and more common, most of which are mediated by IgE antibodies and manifest as urticaria, asthma, diarrhea, and ...suljettu -
Effect of mode of delivery and infant's age on the fatty acid composition of human milk
(09.06.2020)Human milk is the sole source of nutrition for a growing infant. It has all the nutrients the infant needs in the first six months of life. Lipids are the component in milk that supply the infant with approximately 50 % ...suljettu -
Effect of triacylglycerol structure of docosahexaenoic acid (DHA) in the feed on the lipids of livers in rats
(06.11.2019)Dietary lipids, predominantly triacylglycerols (TAGs) of seafood sources provide long-chain omega-3 polyunsaturated fatty acids [LC (n-3) PUFAs] which participate in numerous physiological functions in the body. Docosahexaenoic ...suljettu -
EFFECTS OF BERRY ADDITIVES AND SYNTHETIC ANTIOXIDANTS ON LIPID OXIDATION OF BALTIC HERRING (Clupea harengus membras) FISH MASS DURING COLD STORAGE
(27.07.2020)Baltic herring has great nutritional value due to its high levels of long chain omega-3 polyunsaturated fatty acids (PUFAs). However, this trait also makes Baltic herring susceptible to lipid oxidation. Industrial processes, ...suljettu -
Effects of texture of baby food potatoes on the processing
(23.04.2019)The texture of the potatoes in the baby food is important because with the suitable potato cultivars for the processes the consumer expectations for right product texture can be met. Nestle Finland, Turku Factory produces ...suljettu -
Effects of vitamin B3 supplementation on NAD+ biosynthesis and mitochondrial metabolism in human muscle and white adipose tissue
(22.05.2020)The complex pathophysiology of obesity-related disturbances is closely linked to mitochondria malfunction. Therefore, boosting mitochondrial activity could protect from metabolic complications. Based on animal studies, an ...suljettu -
Elintarvikeprosessien sivuvirtojen hyödyntäminen - Entsyymikäsitellyn panimomäskin ja rypsiöljyn puristejäännöksen kemiallinen koostumus
(22.05.2020)Elintarviketeollisuudessa syntyy runsaasti erilaisia sivuvirtoja, joiden hyödyntämiselle on tarvetta. Tällaisia runsaita sivuvirtoja ovat mäski panimon keittohuoneprosessista ja rypsin puristekakku rypsiöljyn valmistuksesta. ...suljettu -
Expanded genetic code and Effect of synonymous mutations on expression of Fab fragments
(13.12.2019)Antigen binding fragment (Fab) is the part of an antibody which contains an antigen binding site. Fab has many advantages over a conventional antibody such as the reduced size, lack of glycosylation and therefore, ...suljettu -
Extracellular vesicles as a source for non-invasive prostate cancer biomarkers
(21.04.2022)Prostate cancer (PCa) is the third most frequent cancer diagnosis worldwide. Lack of specificity and sensitivity in the current “golden standard” diagnostic approach has motivated researchers to look for new biomarkers, ...suljettu -
Generation of Knock-Out lines for actin cytoskeleton regulators (FCHSD2 and FGD2), and their role in B cells
(06.03.2019)B lymphocytes are cells of the immune system that produce variety of antibodies. Antigen binding to B cell receptor (BCR) leads to transmembrane signaling and antigen internalization. B cell presents internalized antigen ...suljettu -
Glycovariant Enabled Diagnosis of Renal Cell Carcinoma
(24.06.2019)Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary cancers. Each year, around 273, 000 new cases are diagnosed. Prognosis for patients diagnosed with RCC is dependent on the stage when it is ...suljettu -
Hedelmäpuunsyövän (aiheuttaja Neonectria ditissima) tartunnan puolustusyhdisteet omenapuussa
(06.05.2020)Neonectria ditissima -sieni aiheuttaa tarhaomenapuulla (Malus domestica) tautia nimeltä hedelmäpuunsyöpä (lehtipuunkoro). Millään omenapuun lajikkeella ei ole havaittu täydellistä kestävyyttä, mutta eri lajikkeilla on eroja ...suljettu -
HiChIP-menetelmän käyttöönotto leukemiasolujen kromatiinivuorovaikutusten tutkimiseksi
(02.05.2019)Akuutti lymfaattinen leukemia (ALL) on yleisin lasten syöpätyyppi, johon sairastuu Suo-messa vuosittain n. 40 lasta. ALL:n taustalla ovat muutokset solujen kehitystä säätelevien geenien toiminnassa. Tiedetään, että geenien ...suljettu -
High-throughput optimization and transfer of binding kinetics assays from BioLayer Interferometry platforms to Surface Plasmon Resonance
(25.04.2019)Biologics are pharmaceutical drug products whose active drug substance is produced in a living organism by means of recombinant DNA technology. Therapeutic antibodies, which covers roughly a third of the approved biologics, ...suljettu -
Homogeeninen PCR-monianalyyttimääritys SMA-, SCID- ja XLA-oireyhtymien seulontaan
(10.04.2019)Selkäydinperäinen lihassurkastuma (engl. spinal muscular atrophy, SMA) on sairaus, jossa selkäytimen liikehermosolujen toiminta heikkenee, ja potilaalla esiintyy lihasheikkoutta sekä lihasten surkastumista. Pahimmillaan ...suljettu -
Humalan α- ja β-happojen sekä ksantohumolin preparatiivisen nestekromatografiamenetelmän optimointi, yhdisteiden vaikutus GABAA-reseptorin aktiivisuuteen sekä niiden karvaan maun kynnysarvot
(12.11.2019)Humala on yksi oluen pääraaka-aineista. Alun perin sitä käytettiin säilöntäaineena, mutta nykyään sen sisältämien α- ja β-happojen aiheuttamasta karvaasta mausta on tullut yksi oluen tärkeimmistä piirteistä. GABA, eli ...suljettu -
Hunajaviinien fermentointi ja kemiallinen koostumus
(20.12.2019)Hunajaviini on ikivanha alkoholijuoma, jota fermentoidaan hiivalla hunajasta ja vedestä. Suomessa se tunnetaan paremmin nimellä sima, jota usein valmistetaan ruskeasta sokerista hunajan sijaan. Saccharomyces-suvun hiivalajit ...suljettu -
Image-based isolation of single cells for sequencing
(25.05.2020)Cancer is a complex disease characterized by unregulated cell division, resistance towards cell death, activated tissue invasion and the ability to metastasize. Tumors typically display heterogeneous mixture of cancer cells ...suljettu