Selaus laitoksen mukaan kokoelmassa Pro gradu -tutkielmat ja diplomityöt sekä syventävien opintojen opinnäytetyöt (rajattu näkyvyys) Biolääketieteen laitos
Aineistot 21-40 / 107
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Cross-calibration of human PET scanners with phantom studies
(31.10.2023)In the field of medical imaging currently, the speed of the technological advancements in camera design, characteristics, and performance between the Positron Emission Tomography (PET) systems varies considerably. The ...suljettu -
Current overweight but not history of gestational diabetes characterises lifestyle habits in a nationwide cohort of pregnant women
(15.09.2020)The prevalence of overweight and gestational diabetes (GDM), glucose intolerance first manifesting during pregnancy, are increasing. Both are known to predispose mother and child to health complications. The aims of the ...suljettu -
Determinants of serum EPA and DHA in four serum lipid fractions during pregnancy
(05.04.2023)Objective Mother’s blood serum fatty acids are important factors in foetal development. Especially docosahexaenoic acid (DHA) is necessary to neural development. Fish is a great dietary source of DHA and also eicosapentaenoic ...suljettu -
Development and characterization of human cardiac microtissues for a microphysiological multi-organ system
(12.06.2020)Better research models are needed to overcome the lack of translatability from preclinical studies into the clinical phase and to increase the success rates in drug development. Microphysiological systems (MPS) are potential ...suljettu -
Development of Complaint Monitoring Method for Levonorgestrel Intrauterine System Products
(30.06.2023)The central purpose of quality and risk management in pharmaceutical industry is to protect the safety of the population using the medicinal products. Complaint management is essential part of quality and risk management ...suljettu -
Development of in vitro test battery to predict toxicity of indoor air
(02.05.2019)The impurities of the air inside the buildings and the resulting health issues have become an increasing problem. Impurities of indoor air may cause various symptoms, such as respiratory symptoms, nausea, fatigue and memory ...suljettu -
Diet and physical activity of primary school aged children and their association with child's overweight and obesity
(26.03.2021)Abstract Background: Overweight and obesity are common problems in children. it is significantly affected by lifestyles such as nutrition and physical activity. parental obesity as well as activity and family socioeconomic ...suljettu -
Dietary Intake in Relation to the Risk of Developing Gestational Diabetes
(17.04.2020)BACKGROUND Gestational diabetes (GDM) may predispose both the mother and her child to unfavorable health effects. Previous studies indicate that early pregnancy diet could explain the development of GDM in late pregnancy, ...suljettu -
DNA repair genes in prostate cancer : the characterization of novel molecular mechanisms
(18.05.2020)Prostate cancer is one of the major causes of cancer-related deaths in males in Western countries. Androgen deprivation therapy is a standard treatment for metastatic prostate cancer, aiming to suppress androgen receptor ...suljettu -
Effectiveness and drug survival of biologic drugs in the treatment of juvenile idiopathic arthritis
(03.05.2021)Data on treatment performance in real-life setting is needed to supplement the data gained in randomised clinical trials. Variety of registries are increasingly exploited to provide real-world data on effectiveness and ...suljettu -
Effects of 27-hydroxycholesterol on oligodendrocytes in Alzheimer’s disease: a double-edged sword?
(04.05.2020)Hypercholesterolemia is an established risk factor for developing Alzheimer’s disease (AD). A proposed link between elevated systemic cholesterol levels and AD is oxysterols: oxidized metabolites of cholesterol, which can ...suljettu -
Effects of Nanomaterial-Delivered Protein Kinase A on Human Breast Cancer Stem Cells
(06.05.2020)The cancer stem cell (CSC) theory has been proposed as a viable explanation for the resistance of cancer cells to treatments such as radiotherapy and chemotherapy in clinical setting. Emerging studies indicate that ...suljettu -
Evaluation of Scan® 4000 Ultra-HD automatic colony counter
(13.04.2021)Enumeration of colonies manually or automatically provides a principle method for monitoring microbiological purity. Automated colony counter has potential to bring many advantages into microbiological laboratory, including ...suljettu -
Ex vivo characterization of joint innervating neurons in osteoarthritic rodent pain model
(28.08.2023)Osteoarthritis (OA) is the most common joint disease worldwide, affecting an estimate of 240 million people. The predominant symptom of OA is pain. Pain perception arises from nociceptive signals in the periphery, that ...suljettu -
Exercise-induced mobilization of white blood cells in breast cancer patients
(24.04.2023)Acute exercise causes mobilization of the immune cells in healthy individuals, but the phenomenon is less investigated in cancer patients. Exercise-induced mobilization of leukocytes may have positive effects in cancer ...suljettu -
Exploring minimally invasive approach to define stages of type 1 diabetes remotely
(06.07.2022)The purpose of this study was to study the use of continuous glucose monitoring (CGM) in children who have a high lifetime genetic risk for developing type 1 diabetes. We wanted to find out if the different stages of type ...suljettu -
Extracellular vesicles as a source for non-invasive biomarkers from human urine and serum for the early diagnosis of urological cancers
(17.08.2022)Introduction: Urological cancers-particularly cancer in prostate, bladder as well as renal organs- are one of the major causes of morbidity and mortality worldwide. Although treatment of urological cancers has expanded in ...suljettu -
Farmakokineettisten geenimuunnosten vaikutus liitännäislääkehoitona annetun dosetakselin aiheuttaman neutropenian riskiin ja hoidon tehoon suomalaisilla rintasyöpään sairastuneilla naisilla
(04.10.2018)Rintasyöpä on naisten yleisin syöpätyyppi ja Suomessa siihen sairastui vuonna 2015 yli 5000 naista. Suuri osa rintasyöpään sairastuneista saa leikkauksen jälkeen riskiarvion mukaan liitännäishoitona lääke- tai/ ja sädehoitoa. ...suljettu -
Functional characterization of a humanized anti-Clever-1 antibody targeting monocytes and anti-inflammatory macrophages
(29.11.2018)Targeting the immunosuppressive tumor microenvironment has gained interest in opening new avenues to fight against cancer growth. Macrophages are extremely potential candidates for targeted therapies due to their highly ...suljettu -
Functional Characterization of NF1 Deficient Breast Cancer
(16.11.2020)Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with an incidence of 1:2,000. NF1 is caused by pathogenic variants of the tumor suppressor gene NF1. The NF1 syndrome increases cancer incidence and is ...suljettu