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Evaluation of variant calling tools for detecting structural variants using real and simulated genomic datasets
Structural variants are generally defined as DNA variations larger than 50bp. They have been recognized as the largest source of inter-individual genetic variation and shown to play an important role in human life. Genomic ...
The properties of the last universal common ancestor
The last universal common ancestor is believed to be an organism from which all modern organisms on earth today are thought to be descended from. LUCA is thought to be the recent most ancestor to all present-day organisms ...
Comparison of de novo metagenomic assembly tools
The field of metagenomics involves studying the composition and function of microbial communities via isolated DNA from a variety of environments like soil, water and the human gut. Since the current generation sequencing ...