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Pancreatic cancer is among the most lethal malignancies. Cancer antigen 19.9 is the most used and best-validated serum tumor marker for PanCa diagnosis. However, several critical aspects impede its clinical use, such as ...

Low level of pregnancy-associated plasma protein-A (PAPP-A) in serum during pregnancy is associated with pregnancy abnormalities, such as Down’s syndrome, miscarriage and ectopic pregnancy. PAPP-A exist in two different ...

Lung cancer (LC) is the second most prevalent cancer, and it has the highest mortality rate of all cancers globally in both genders. There are several treatment options for LC, but patients often develop resistance to ...

The aim of this thesis was to gain knowledge on solid state fermentation on raspberry and black currant leaves. The focus was on the possible increase in polyphenol content and in particular flavonols. The knowledge ...

Lugdunomycin, a novel antibacterial natural product isolated from Streptomyces sp. QL37, is a highly rearranged angucycline-derived polyketide with strikingly complex structure. Its proposed biosynthetic pathway involves ...

Silakka (Clupea harengus membras) on sillin alalaji ja Suomen taloudellisesti merkittävin kalalaji, joka elää erityisesti Itämeren pohjoisemmissa osissa. Ruokakalana silakka on hyvin ravinteikasta, mutta silakoiden laadun ...

In vitro -diagnostiikkaan tarkoitettujen lääkinnällisten laitteiden lainsäädäntö Euroopassa uudistuu, kun IVD-asetus (IVDR) astuu voimaan 26.5.2022. Laitteille asetetaan riskiluokitukseen perustuen laatu-, suorituskyky ja ...

The human microbiome – which refers to microbes living in a human along with their metabolites – has received increasing attention in recent years. "Our second genome" is associated both with numerous diseases and also ...

Biotuotannossa käytettävät bakteerikannat hyötyvät parantuneesta stressinsietokyvystä. Tässä tutkimuksessa syanobakteerin stressinsietoa yritetään parantaa muuttamalla RNApolymeraasin toimintaa. Syanobakteerien ...

Aggregatibacter actinomycetemcomitans on gram-negatiivinen, opportunistinen suupatogeeni, joka kasvaa hampaan pinnalla biofilminä aiheuttaen kroonista tulehdusta, parodontiittia. A. actinomycetemcomitansin patogeenisuus ...