Hae
Aineistot 1-1 / 1
Part 1: The role of amyloid fibrils in protein aggregation diseases and molecular therapy. Part 2: Isolation of single-chain Fraction variable antibodies that bind to the toxic 8 kDa-fragment of gelsolin using phage display
(2019-09-06)
Gelsolin amyloidosis (Meretoja’s disease) is an inherited disease with slowly developing neuromuscular symptoms. Patient’s carry a mutation leading to misfolding of the gelsolin protein, which initiates an aberrant proteolytic ...