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Aineistot 11-18 / 18
Uncovering the LINC between cytoplasmic keratin 8 and nuclear lamins using 2D and 3D culture systems
(2018-12-04)
Keratins are cytoplasmic intermediate filament (IF) proteins found in epithelial cells where they play a significant role in the protection from mechanical stresses. Keratin mutations have been associated with over 60 human ...
The role of TGFβ signaling in lymphatic endothelial sprout formation
(2020-11-25)
Lymphatic vasculature consists of complex treelike lymphatic vessel networks formed by lymphatic endothelial cells (LECs). The lymphatic vessel network expands via sprouting of LECs from the existing network, i.e. via ...
The Role of Arginine Vasopressin (AVP) during Birth Asphyxia
(2021-08-27)
During normal vaginal birth, a surge of the stress hormone arginine vasopressin (AVP) occurs in the periphery that helps the fetus to quickly adjust to extrauterine life. During complicated birth such as mild birth asphyxia, ...
The effects of the combination treatment of AR and FGFR inhibitors in prostate cancer
(2021-05-18)
Androgen receptor (AR) signaling is key for prostate cancer (PrCa) progression. Androgen deprivation therapy is not curative if PrCa progresses to advanced, castration-resistant PrCa and androgen-independent cancers. ...
The Role of Vimentin in the YAP signaling in Wound Healing and Cancer Invasion
(2023-05-30)
Vimentin, a crucial cytoskeletal protein, plays a role in wound healing and cancer
progression. However, its precise mechanism is not fully understood. Previous research
has shown a connection between the expression ...
Investigating filopodia formation on fibronectin and cadherin substrates
(2023-08-03)
Cancer metastasis involves cancer cells migrating from primary tumours to distant organs and tissues. Filopodia, slender finger-like protrusions, play a pivotal role in cell migration and interactions with the extracellular ...
A Framework for the Systematic Comparison of Classical Non-Learning, Machine Learning, and Artificial Intelligence Approaches to Cell Segmentation & Nuclei Detection in Histopathological Images
(2023-08-03)
In the fields of diagnosis, digital pathology, and drug discovery, the characterization of tissue, in particular the cells, is crucial because it provides a fundamental understanding of the underlying cellular dynamics and ...
Cross-calibration of human PET scanners with phantom studies
(2023-10-31)
In the field of medical imaging currently, the speed of the technological advancements in camera design, characteristics, and performance between the Positron Emission Tomography (PET) systems varies considerably. The ...