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Non-genetic rewiring of ERBB signaling in cancer drug tolerance
(2022-05-11)
ERBB receptors are transmembrane receptor tyrosine kinases (RTKs) that are activated by dimerization and intracellular tyrosine phosphorylation upon ligand binding. The ERBB family includes EGFR, ERBB2, ERBB3, and ERBB4 ...
Akkermansia muciniphilan ja Citrobacter rodentiumin vastakkaiset vaikutukset autoimmuunidiabeteksen kehittymiseen NOD-hiirellä
(2022-05-11)
Tyypin 1 diabeteksessa haiman Langerhansin saarekkeiden insuliinia tuottavat betasolut
tuhoutuvat autoimmuunireaktiossa, jolloin glukoositasapainon ylläpito estyy. Antigeeniä
esittelevät solut (APC, antigen presenting ...
Designing a quantitative PCR assay for fetal RhD genotyping from maternal plasma derived cell-free fetal DNA
(2022-05-17)
Hemolytic disease of the fetus and newborn (HDFN) is typically caused by maternal alloimmunization against antigens of RhD positive red blood cells. During pregnancy, these anti-RhD antibodies can induce the destruction ...
A Rapid Approach To Web Application Security
(2022-06-10)
After using and developing a web application tool at a company, it is now time for this tool to be productised and made available for use to external customers. Initially, as this was the company’s R&D internal tool, the ...
Sensory Characterisation and Chemical Composition of Alcoholic Pear Beverages
(2022-01-07)
Perry, or pear cider, is a fermented beverage made from the juice of varieties of pears. Alcoholic pear beverages or pear ciders have not been investigated that widely and there are no available data on utilization of ...
Adaptive Web UI for Modular diagnostics service
(2022-04-26)
To do a Web-based service, there are several architectures and software tools for choose from. Also, nearly as many frameworks that can implement a graphical user interface for the service. This thesis involves studying ...
DevOps in regulated environment
(2022-05-07)
This thesis is done to examine the suitability, advantages and challenges of DevOps working model within Wallac Oy software units. The company designs and manufactures analysis equipment, instruments, reagents, assay ...
Evaluating Procedurally Generated Levels : Developing metrics for 3D platforming challenges
(2022-05-11)
Evaluating the quality of procedurally generated outputs is still one the important open problems in the field of Procedural Content Generation (PCG). This paper presents an evaluative model for assessing 3D platformer ...
Anti-nukleoproteiinivasta-aineen affiniteetin parantaminen geenitekniikan keinoin ja koronavirusmäärityksen kehittäminen kuoppalevyformaatissa
(2022-04-06)
Covid-19 diagnosoimiseksi on kehitetty antigeenitestejä. Ne ovat PCRmenetelmää nopeampia ja halvempia, mutta kärsivät usein alhaisesta herkkyydestä. Työssä tuotettiin ja paranneltiin vasta-aineita, jotta saavutettaisiin ...
Effects of high-fat diet-induced obesity on sperm small RNA profile and offspring phenotype in mice
(2022-06-09)
Paternal obesity has not only adverse effects on exposed individuals, but it can also induce metabolic changes in offspring through epigenetic inheritance. High-fat diet (HFD) affects sperm’s small non-coding RNA (sncRNA) ...