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Aineistot 51-60 / 109
The effect of alcohol hangover and residual zopiclone on spatial perception and driving skills
(2019-03-28)
Driving a vehicle in a state of alcohol hangover, or with residual sedatives and hypnotics, is a frequently occurring situation. Zopiclone is the most commonly used hypnotic in Finland, often taken in the middle of the ...
Breast cancer prevention by diet : The effect of dietary polyphenols on TNF-α mediated aromatase gene (CYP19A1) expression in breast stromal cells
(2021-05-24)
The different ways to prevent postmenopausal breast cancer have been under investigation for years. The effects of menopause and obesity-related adipose tissue inflammation on estrogen biosynthesis are believed to promote ...
Effectiveness and drug survival of biologic drugs in the treatment of juvenile idiopathic arthritis
(2021-05-03)
Data on treatment performance in real-life setting is needed to supplement the data gained in randomised clinical trials. Variety of registries are increasingly exploited to provide real-world data on effectiveness and ...
The mouth-throat models and inspiratory flow profiles in in vitro analytics of dry powder inhalers
(2021-09-23)
Dry powder inhalers (DPI´s) are devices that operate by converting the powder into an aerosol form and release particles for the lung deposition. DPI´s can be characterized using aerodynamic particle size distribution ...
Analysis of Rab24 protein expression in mouse tissues
(2020-05-06)
Rab24 belongs to the Rab family of small GTPases that play important roles in intracellular vesicle formation, transportation, and fusion with target compartments. Almost 70 Rab proteins have been identified in humans so ...
Ravintolisien käyttö on yleistä ja poikkeaa suositellusta raskaana olevilla
(2020-09-27)
Raskauden aikana energian ja ravintoaineiden tarve kasvaa. Monipuolinen ja energiamäärältään riittävä ruokavalio täyttää suurimman osan ravintoaineiden lisätarpeesta, mutta lisäksi tarvitaan myös muutamia ravintolisiä. ...
Development and characterization of human cardiac microtissues for a microphysiological multi-organ system
(2020-06-12)
Better research models are needed to overcome the lack of translatability from preclinical studies into the clinical phase and to increase the success rates in drug development. Microphysiological systems (MPS) are potential ...
Effects of 27-hydroxycholesterol on oligodendrocytes in Alzheimer’s disease: a double-edged sword?
(2020-05-04)
Hypercholesterolemia is an established risk factor for developing Alzheimer’s disease (AD). A proposed link between elevated systemic cholesterol levels and AD is oxysterols: oxidized metabolites of cholesterol, which can ...
DNA repair genes in prostate cancer : the characterization of novel molecular mechanisms
(2020-05-18)
Prostate cancer is one of the major causes of cancer-related deaths in males in Western countries. Androgen deprivation therapy is a standard treatment for metastatic prostate cancer, aiming to suppress androgen receptor ...
Current overweight but not history of gestational diabetes characterises lifestyle habits in a nationwide cohort of pregnant women
(2020-09-15)
The prevalence of overweight and gestational diabetes (GDM), glucose intolerance first manifesting during pregnancy, are increasing. Both are known to predispose mother and child to health complications. The aims of the ...