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Aineistot 61-70 / 107
Avohoidon MRSA-tapausten epidemiologia Turun alueella vuosina 2007-2016
(2021-02-01)
Tämän syventävien opintojeni kohteeksi valikoitui avohoidon MRSA-tapaukset Turussa vuosina 2007-2016. Opinnäytetyöni on osa laajempaa TY:ssa ja VSSHP:ssa käynnissä olevaa MRSA-tutkimushanketta. MRSA-infektiot aiheuttavat ...
Novel approaches for ErbB receptor tyrosine kinase inhibition
(2020-12-14)
ErbB receptor tyrosine kinases are cell-surface proteins that regulate cell proliferation, differentiation, and survival. The four ErbB family members – EGFR, ErbB2, ErbB3 and ErbB4 – function abnormally in certain types ...
Neurofibrooman makrofagit
(2021-02-10)
Tyypin 1 neurofibromatoosi (NF1) on autosomaalisesti ja vallitsevasti periytyvä oireyhtymä. Lähes kaikilla aikuisilla NF1-potilailla on ihon neurofibroomia, jotka muodostuvat hermon tukikudoksen soluista ja runsaasti ...
Vimentin and actin interplay in the osteoclast life cycle
(2021-03-15)
Osteoclasts are large, multinucleated bone resorbing cells that partake in the process of bone remodelling, which is vital for skeletal growth, injury repair and overall bone homeostasis. They achieve their function through ...
Blocking Clever-1 on human monocytes inhibits the growth of aggressive breast cancer
(2019-07-31)
Immunosuppressive tumor microenvironment limits antitumoral immunity and facilitates cancer progression. Tumor-associated macrophages that are mainly derived from blood monocytes, are central regulators of the tumor immune ...
Evaluation of Scan® 4000 Ultra-HD automatic colony counter
(2021-04-13)
Enumeration of colonies manually or automatically provides a principle method for monitoring microbiological purity. Automated colony counter has potential to bring many advantages into microbiological laboratory, including ...
Reproductive analysis of HSD17B3 knockout mice
(2019-01-08)
Hydroxysteroid (17β) dehydrogenase type 3 (HSD17B3) is known to be the primary enzyme responsible for the conversion of androstenedione to testosterone in testes, and thus important for male sexual development, maturation ...
Androgen-oestrogen imbalance, obesity, and intestinal microbiota in AROM+ male mice
(2021-03-17)
Androgens and oestrogens are sex hormones that produce sex-specific characteristics in males and females, respectively. However, sex hormones also possess far-reaching metabolic effects, which is evident in the comorbidity ...
The role of PLVAP protein in endothelial cells of liver
(2021-02-09)
In endothelial cells (EC) PLVAP protein forms permeability regulating structures known as diaphragms. In some previous studies it has been stated that PLVAP does not exist in adult liver ECs, because diaphragms of liver ...
Unraveling significance of receptor-ligand interaction on Jagged1 mobility, filopodia and ligand clustering in the Notch signaling pathway
(2019-08-02)
The Notch signaling pathway plays a crucial role in many diseases. It has been proven that the Notch pathway is involved with several human cancers, including T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma. It ...