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Diet and physical activity of primary school aged children and their association with child's overweight and obesity
(2021-03-26)
Abstract
Background: Overweight and obesity are common problems in children. it is significantly affected by lifestyles such as nutrition and physical activity. parental obesity as well as activity and family socioeconomic ...
Self-reported healthy dietary behavior relates to parental attitudes on child feeding, health and diet quality.
(2021-03-22)
Parents influence their children´s diet greatly as seen in earlier research. In addition, it
is known that both diet and obesity in childhood tend to persist and therefore affect to
the risk of several chronic lifestyle ...
Identification of RasGEFs counteracting neuronal SynGAP1 function
(2021-05-11)
SynGAP syndrome refers to an under-diagnosed group of diseases caused by the mutation of the SynGAP1 gene encoding the predominant synaptic protein SynGAP1. SynGAP1 is a Ras GTPase activating protein that is a major regulator ...
In Search of Ebola Virus Glycoprotein Inhibitors: A Structure-Based Drug Design Study
(2021-03-05)
Ebola virus (EBOV) is one of the deadliest viruses that causes haemorrhagic fever in humans and the fatality rate is more than 50%. The biggest outbreak of Ebola virus disease (EVD) occurred in 2014-2016 in West Africa ...
Uncovering the LINC between cytoplasmic keratin 8 and nuclear lamins using 2D and 3D culture systems
(2018-12-04)
Keratins are cytoplasmic intermediate filament (IF) proteins found in epithelial cells where they play a significant role in the protection from mechanical stresses. Keratin mutations have been associated with over 60 human ...
ORIGINS OF ANTIBODY DIVERSITY AND THE ROLE OF BACH2 IN SOMATIC HYPERMUTATION
(2021-03-16)
Antibodies produced by B cells are critical for our immunological defence against pathogens. For antibodies, the ability to recognise and bind pathogenic antigens improves through time during infection. Improvement is due ...
The role of TGFβ signaling in lymphatic endothelial sprout formation
(2020-11-25)
Lymphatic vasculature consists of complex treelike lymphatic vessel networks formed by lymphatic endothelial cells (LECs). The lymphatic vessel network expands via sprouting of LECs from the existing network, i.e. via ...
The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration
(2020-12-14)
ERBB4 is a cell surface receptor that belongs to the ERBB family of receptor tyrosine kinases. Binding of a ligand to the extracellular domain leads to the activation of the intracellular kinase domain and autophosphorylation ...
Hermoston toiminnan kertaus ennen neurofarmakologian opiskelua
(2021-09-17)
Lääketieteen lisensiaatin koulutusohjelmassa tiedon kumuloituminen on olennainen osa opintoja. Aluksi opiskellaan kehon normaalia toimintaa, jonka pohjalta opiskellaan sairauksien patologiaa sekä niiden hoitoa. Ensimmäisinä ...
The Role of Arginine Vasopressin (AVP) during Birth Asphyxia
(2021-08-27)
During normal vaginal birth, a surge of the stress hormone arginine vasopressin (AVP) occurs in the periphery that helps the fetus to quickly adjust to extrauterine life. During complicated birth such as mild birth asphyxia, ...