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    • Halogen hectorites : smectites designed to luminesce 

      Santos, Hellen Silva
      Turun yliopiston julkaisuja. Sarja AI: Astronomica - Chemica - Physica – Mathematica : 571 (Turun yliopisto, 15.12.2017)
      The smectites represent a versatile class of clay minerals, offering possibilities of applications in several industrial and scientific fields. The hectorite belongs to this class, but it has the advantage of production ...

    • Highlighting the chemical diversity of plants: modern tools for chemistry education 

      Manninen, Marianna
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Mathematica : 673 (Turun yliopisto, 28.10.2022)
      The chemical diversity of plants is enormous as plants produce a variety of compounds that play key roles, for instance, in the growth, defence and reproduction of plants. This diversity is not well recognised in chemistry ...

    • Hydrophobicity and lipid interactions of hydrolysable tannins 

      Virtanen, Valtteri
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 699 (Turun yliopisto, 29.09.2023)
      This thesis work focused on a specialized plant metabolite group called hydrolysable tannins with the aim of expanding the knowledge on their hydrophobicity, interactions with lipid membranes and antibacterial capacity. ...

    • Label-free methods for studying protein-protein interactions 

      Valtonen, Salla
      Turun yliopiston julkaisuja -Annales Universitatis Turkuensis AI: Astronomica - Chemica- Phsysica : 661 (Turun yliopisto, 17.12.2021)
      Proteins are the building blocks of life, and mainly perform their roles through protein-protein interactions (PPIs). Thus, PPIs are essential to the normal function of the cells and the body, and disturbances in these ...

    • Lanthanide doped NaYF4 up-conversion luminescence materials 

      Laihinen, Tero
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 550 (Turun yliopisto, 14.12.2016)
      The thesis includes literature and experimental parts. The first part introduces the reader to the topic while the later part contains synthesis and characterization details, results and publications. Up-conversion (UPC) ...

    • Metal-Ion-Binding Oligonucleotides: High-Affinity Probes for Nucleic Acid Sequences 

      Taherpour, Sharmin
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 523 (Turun yliopisto, 23.10.2015)
      Small non-coding RNAs have numerous biological functions in cell and are divided into different classes such as: microRNA, snoRNA, snRNA and siRNA. MicroRNA (miRNA) is the most studied non-coding RNA to date and ...

    • Modifying upconverting nanoparticles with polyelectrolyte multilayers 

      Palo, Emilia
      Turun yliopiston julkaisuja. Sarja A I: Astronomica – Chemica – Physica – Mathematica : 602 (Turun yliopisto, 12.04.2019)
      Upconversion luminescence where visible light can be obtained through low energy near-infrared radiation is an interesting research topic especially within the scope of biomedical applications using optical detection. The ...

    • Monitoring cellular Guanosine triphosphate (GTP) and GTP associated proteins 

      Mahran, Randa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis AI: Astronomica, Chemica, Mathematica : 707 (Turun yliopisto, 01.03.2024)
      Guanosine-5'-triphosphate (GTP) is an essential molecule for cell survival and function. Although free GTP plays a crucial role in several cellular processes, most studies focus solely on the protein bound GTP and its ...

    • NIR-Vis Up-Conversion Luminescence in the Yb3+,Er3+ Doped Y2O2S, ZrO2, and NaYF4 Nanomaterials 

      Pihlgren, Laura
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 502 (Turun yliopisto, 16.12.2014)
      Since the discovery of the up-conversion phenomenon, there has been an ever increasing interest in up-converting phosphors in which the absorption of two or more low energy photons is followed by emission of a higher energy ...

    • Novel 19F NMR sensors for the characterization of higher-order secondary structures of DNA and RNA 

      Granqvist, Lotta
      Turun yliopiston julkaisuja. Sarja AI: Astronomica – Chemica – Physica – Mathematica : 580 (Turun yliopisto, 14.06.2018)
      Both DNA and RNA can fold into a variety of non-canonical structures. Non-canonical structures, such as triplexes and G-quadruplexes, are an active research area due to their biological significance and therapeutic potential. ...

    • Nucleotides as Antiviral Compounds. On the Feasibility of an Esterase-dependent Prodrug Strategy for 2-5A 

      Kiuru, Emilia
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 516 (Turun yliopisto, 05.06.2015)
      Nukleotidien ja oligonukleotidien analogeilla on merkittävä rooli virusten aiheuttamien tautien hoidossa. Tämän kaltaiset yhdisteet voivat estää spesifisesti virusten proteiineja tai aktivoida luontaista immuunijärjestelmää, ...

    • Oligomeric Ellagitannins of Epilobium Angustifolium : Quantification and Bioactivity Assessment 

      Baert, Nicolas
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 564 (Turun yliopisto, 18.08.2017)
      Over the past few years there has been a growing body of evidence highlighting the fact that tannin-rich fodders could be beneficial to animal welfare as well as to the environment, by decreasing methane emissions from ...

    • Organomercury oligonucleotides as artificial ribonucleases 

      Saleh, Lange Yakubu
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser AI: Astronomica - Chemica - Physica – Mathematica : 710 (Turun yliopisto, 10.05.2024)
      Antisense oligonucleotides (ASOs) leverage the natural catalytic activity of RNases H to target specific RNA sequences for degradation. However, the challenge lies in incorporating chemical modifications into ASOs to enhance ...

    • Oxidative multilayer films and eumelanin analogs for biocompatible supercapacitors 

      Marttila, Lauri
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Mathematica : 681 (Turun yliopisto, 16.12.2022)
      The future applications of implantable electronic medical devices set heavy requirements for the materials powering the devices. They need to be biocompatible or even biodegradable and have sufficient electrochemical ...

    • Peptide-based drug discovery tools for protein post-translational modifications 

      Eskonen, Ville
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 642 (Turun yliopisto, 26.02.2021)
      Bringing a new drug to the market is an expensive and long process. Typically, more than ten years and a billion dollars needs to be spent so the whole process is a big investment for a pharma company. The hit generation ...

    • Phenolics of the Inner Bark of Silver Birch: Characterization and Intraspecific Variation 

      Liimatainen, Jaana
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 477 (Turun yliopisto, 13.12.2013)
      This thesis describes work related to the in-depth characterization of the phenolic compounds of silver birch (Betula pendula) inner bark. Phenolic compounds are the most ubiquitous class of plant secondary compounds. The ...

    • Photoluminescence quenchers in drug discovery 

      Vuorinen, Emmiliisa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 659 (Turun yliopisto, 03.12.2021)
      During the drug discovery process molecular libraries containing millions of molecules are screened to find a single potential drug with the highest potency and efficacy over unwanted side-effects. The whole drug development ...

    • Polyviologens: Electrochemical Synthesis and Characterization 

      Wang, Nianxing
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 547 (Turun yliopisto, 14.10.2016)
      Microelectronics and flexible electronics are applications that have attracted more and more attention in the today’s world. The research of these kinds of electronics requires the development and improvement of ...

    • Prodrug strategies of antiviral nucleotides: Studies on enzymatically and thermally removable phosphate protecting groups 

      Leisvuori, Anna
      Turun yliopiston julkaisuja. Sarja AI, Chemica - Physica – Mathematica : 522 (Turun yliopisto, 18.09.2015)
      Antiviral nucleosides are compounds that are used against viruses, such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). To act as therapeutic agent, the antiviral nucleoside needs to be phosphorylated ...

    • Radiosynthesis of [¹⁸F]F-DPA with various molar activities for the imaging of neuroinflammation 

      Keller, Thomas
      Turun yliopiston julkaisuja. Sarja A I: Astronomica – Chemica – Physica – Mathematica : 607 (Turun yliopisto, 14.06.2019)
      The use of radioisotopes as a means to non-invasively look into living subjects influenced both diagnostic and therapeutic medicine in the past century. Nowadays positron emission tomography (PET), employing short-lived ...