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Disorders of male reproductive health are becoming increasingly prevalent due to unknown reasons. Pharmaceutical agents and environmental chemicals can cause adverse effects on the reproductive system, but reproductive ...

ABSTRACT Non-alcoholic fatty liver disease (NAFLD), characterized by the accumulation of fat within hepatocytes, has become the most common chronic liver disease in developed countries. NAFLD is associated with insulin ...

Detection and classification of cancer is challenging because current methods are often clinically ambiguous, expensive and/or laborious. Molecular tests have been developed over past decades but they lack accuracy, clinical ...

Taxanes are microtubule targeting chemotherapeutics that block cell division (mitosis) and induce cell death. Taxanes are commonly used in the neoadjuvant chemotherapy for breast and ovarian cancer. However, the patient ...

The study focuses on proteins Securin, Pttg1IP and Separase, involved in metaphase-anaphase transition of mitosis, and microRNAs -494, -205, -21 and -126 in association with cell proliferation. The aim is to demonstrate ...

Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease traditionally believed to be driven primarily by the adaptive immune cells. However, a large infiltrate of innate cells can be seen in the inflamed ...

ABSTRACT The rise of antibiotic-resistant pathogenic bacteria and the increasing understanding of the beneficial role of the bacterial microbiota, disrupted by antibiotics, prompt the development of new anti-bacterial ...

Male germ cell differentiation, spermatogenesis is an exceptional developmental process that produces a massive amount of genetically unique spermatozoa. The complexity of this process along with the technical limitations ...

Bone tissue is a dynamic organ which undergoes constant remodeling through a coupled series of events in order to maintain proper skeletal structure and calcium-phosphate homeostasis. In addition to its mechanical properties, ...