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Reversible Base-Filling of Oligonucleotides through formation of N-Methoxy-1,3-Oxazinane and -Oxazolidine Nucleosides
(Turun yliopisto, 2025-08-15)
Dynamic combinatorial chemistry (DCC) has emerged as a powerful tool for screening and optimization of lead compounds for the discovery of new drugs. This thesis introduces a novel method for base filling through the ...