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Preclinical development of radiopharmaceuticals for Alzheimer’s disease: Biological evaluation of (S)-[18F]THK5117 and [11C]SMW139 PET tracers in the APP/PS1-21 mouse model of Alzheimer’s disease
(Turun yliopisto, 2024-02-27)
Alzheimer’s disease (AD) pathological cascade is characterised by the formation of β-amyloid peptide (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau (p-tau) in association with neuroinflammation. Positron ...