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Prostate cancer initially responds to hormone-based therapeutics such as anti-androgen treatment or chemotherapeutics but eventually becomes resistant. Novel treatment options are therefore urgently needed. This thesis ...

CBS domains are ~60 amino acid tandemly repeated regulatory modules forming a widely distributed domain superfamily. Found in thousands of proteins from all kingdoms of life, CBS domains have adopted a variety of functions ...

Cyanobacteria are well-known for their role in the global production of O2 via photosynthetic water oxidation. However, with the use of light energy, cyanobacteria can also reduce O2. In my thesis work, I have investigated ...

The central goal of food safety policy in the European Union (EU) is to protect consumer health by guaranteeing a high level of food safety throughout the food chain. This goal can in part be achieved by testing foodstuffs ...

The genetic engineering of cyanobacteria is seen as a promising strategy to develop future photosynthetic microbial cell factories capable of generating carbon-based compounds from water, CO2 and solar energy. This synthetic ...

Allergic diseases including food allergy and eczema in an infant in combination with the everyday activities of caring for a family will pose challenges to parents. Only fragments of these challenges are revealed to health ...

An aging population and increasing rates of diabetes mellitus contribute to a high prevalence of kidney dysfunction – approximately 10 percent of adults in developed countries have chronic kidney disease (CKD). CKD is a ...

In photosynthetic light reactions, photosystem (PS)II and PSI as well as Cytochrome b6f, which are embedded in the thylakoid membrane of chloroplasts, transfer electrons from water molecules to NADP+ using the light energy ...

Cyanobacteria are unique prokaryotic microbes performing oxygenic photosynthesis. They have inherent capacity of the direct conversion of solar energy, CO2 and water into carbonbased compounds. Scientists’ increasing ...

Inorganic pyrophosphatases (PPases) are essential enzymes for every living cell. PPases provide the necessary thermodynamic pull for many biosynthetic reactions by hydrolyzing pyrophosphate. There are two types of PPases: ...