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The number of individuals affected by Type 2 diabetes mellitus (T2DM) is increasing rapidly nearly everywhere in the world. Insulin resistance, which means reduced impact of insulin in its target tissues, especially in the ...

Obesity is a significant and increasing health challenge. Obesity is strongly associated with the incidence of type 2 diabetes (T2D). In obese individuals, liver insulin resistance is a major factor in the development and ...

The global epidemic of obesity is a challenge to healthcare systems due to the increase in the incidence of type 2 diabetes (T2D) and its associated morbidities. Although the small intestine is the first absorptive organ ...

Practical and accurate blood pressure (BP) measurement techniques are needed to ensure adequate diagnostics and treatment of hypertension. Recently, novel monitors have appeared on the market including timer-equipped home ...

Cardiovascular mortality is 20 times higher in patients with chronic kidney disease and 3─5 times higher in patients with a kidney transplant than in the age-matched general population, which is partly explained by endothelial ...

The systemic vasculitides are characterized by inflammation of the blood vessel walls. Most vasculitides are idiopathic but sometimes a triggering event, e.g., medication, can be identified. Vessels of any type and size ...

Total energy intake, physical activity, body size and body composition determine total energy expenditure. An imbalance between total energy intake and total energy expenditure causes obesity. Overweight and obesity remains ...

The association of conventional childhood and adulthood cardiometabolic risk factors and adulthood socioeconomic status with adulthood cardiometabolic health is well-established. However, the association between childhood ...

We are currently facing a global epidemic of obesity, which poses a great challenge for the global health. Insulin resistance is the common soil that links obesity and type 2 diabetes. Whereas most lifestyle interventions ...

The majority of patients with end-stage kidney disease develop abnormalities in bone metabolism, referred to as renal osteodystrophy. Bone abnormalities are associated with cardiovascular morbidity and mortality. The ...