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Role of cancerous inhibitor of protein phosphatase 2A in the regulation of T-cell response
(Turun yliopisto, 2021-12-03)
T helper (Th) cell subsets with distinct functions are a critical component of the adaptive immune system. Th17 cells secrete interleukin 17 (IL-17) and provide host defense against pathogens. However, dysregulated Th17 ...
Immunoregulatory roles of CD73 in lymphatic endothelial and myeloid cells
(Turun yliopisto, 2021-01-29)
The immune system is a fascinating product of the interaction and cooperation of amultitude of cells and tissues. It is thereby able to distinguish between “friend” and “foe” and protect the host from a great variety of ...
Ontogeny and function of adipose tissue macrophages
(Turun yliopisto, 2023-11-03)
ABSTRACT
Macrophages are immune cells that also participate in the development and homeostasis of most tissues. Macrophages can originate during embryonic development, first from the yolk sac and later from the fetal ...
PLVAP as the gatekeeper of endothelial cell permeability and leukocyte migration
(Turun yliopisto, 2019-10-11)
Endothelial cells (EC) line the lymphatic and vascular vessels of the body, forming a barrier between the lumen and surrounding tissue. ECs actively coordinate the exchange of migrating cells, fluids and molecules thus ...
Lyme borreliosis in Finland : studies on environmental exposure, disease susceptibility and epidemiology
(Turun yliopisto, 2017-10-13)
Lyme borreliosis is the most common tick-borne infectious disease in Europe and North America. It is caused by the spirochetes belonging to the Borrelia burgdorferi sensu latocomplex. The bacteria are transmitted to humans ...
Characteristics of anti-pertussis toxin antibodies after vaccination and infection
(Turun yliopisto, 2024-04-12)
Pertussis or whooping cough is a human respiratory tract infection caused by Bordetella pertussis bacteria. Despite extensive vaccinations, pertussis incidence has increased during the last decades. The reasons behind this ...





