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New luminometric particle-based methods were developed to quantify protein and to count cells. The developed methods rely on the interaction of the sample with nano- or microparticles and different principles of detection. ...

Positron emission tomography (PET) is a non-invasive technology widely used in oncology, cardiology, neurology and inflammation imaging. PET can detect the expression of receptors, genes and molecular pathways in both ...

Background: Patients with mental health conditions (MHCs) face barriers in health care and often have undertreated comorbidities. The purpose of this dissertation was to evaluate the treatment and prognosis of patients ...

The myocardium of patients with coronary artery disease (CAD) often is a mixture of ischaemic but viable tissue and irreversibly injured scar tissue. The viable tissue has capability of functional recovery after restoration ...

Cardiovascular disease is the leading cause of high mortality in advanced chronic kidney disease (CKD) patients. Treatment and prevention of cardiovascular disease should be in focus to improve prognosis in this high-risk ...

Hyvän syntymän hoidon tavoitteena on turvata synnyttäjän paras mahdollinen terveys, vähentää tarpeetonta puuttumista synnytyksen kulkuun ja mahdollistaa voimaannuttava synnytyskokemus perheelle. Hyvä syntymän hoito ja ...

Tissue-based biomarkers are studied to receive information about the pathologic processes and cancer outcome, and to enable development of patient-tailored treatments. The aim of this study was to investigate the potential ...

Biocatalysis can be applied in organic synthetic chemistry to counter challenges posed by increased demands towards chemo-, regio- and stereoselectivity, not forgetting the need for greener chemistry. During the last 30 ...

Sharpin (SHANK‐Associated RH Domain Interactor) is a multifunctional adaptor protein that interacts with other proteins and regulates their functions. For example, Sharpin is a subunit of the linear ubiquitination assembly ...

Brown adipose tissue (BAT) is a functional and metabolically active tissue found in humans. Instead of storing energy like white adipose tissue (WAT), BAT dissipates energy in the form of heat in a process called thermogenesis. ...