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Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study
<p>Background: Cardiometabolic health among adult offspring of hypertensive disorders of pregnancy (HDP) is relatively unknown. We hypothesized that offspring of HDP would have abnormalities in the retinal microvasculature ...
Polygenic Hyperlipidemias and Coronary Artery Disease Risk
Background:<div>Hyperlipidemia is a highly heritable risk factor for coronary artery disease (CAD). While monogenic familial hypercholesterolemia associates with severely increased CAD risk, it remains less clear to what ...
Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study
<div>Background</div><div>Studies have shown that osteoporosis and atherosclerosis are comorbid conditions sharing common risk factors and pathophysiological mechanisms. Understanding these is crucial in order to develop ...
Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins
Eicosanoids and related oxylipins are critical, small bioactive mediators of human physiology and inflammation. While similar to 1,100 distinct species have been predicted to exist, to date, less than 150 of these molecules ...
Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery
<h3>Abstract</h3><div><h4>AIMS: </h4><p>To study myocardial substrate uptake, structure and function, before and after bariatric surgery, to clarify the interaction between myocardial metabolism and cardiac remodelling in ...
Extension of Public Smoking Ban Was Not Associated with Any Immediate Effect on Stroke Occurrence in Finland
We investigated the association between the widening of a nationwide restaurant smoking ban, enacted on 1 June 2007, and stroke admissions. All acute stroke admissions between 1 May 2005 and 30 June 2009 were retrieved ...