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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Ahluwalia TS; Ameur A; Balkhiyarova Z; Balslev-Harder MN; Bandinelli S; Bartz TM; Baumeister SE; Beilby J; Bentley AR; Berry D; Bielak LF; Bis JC; Blangero J; Boehnke M; Boomsma DI; Bouchard C; Brage S; Braund PS; Brody JA; Broos S; Bruinenberg M; Chasman DI; Chong M; Chu AY; Cole JW; Collins FS; Cornelis MC; Cupples LA; De Geus EJC; Deldicque L; Den Hoed M; Dorajoo R; Dorr M; Dueker ND; Ekelund U; Emmerich A; Enroth S; Esko T; Evans MK; Faul JD; Feenstra B; Feitosa MF; Fernandez-Rhodes L; Ferrucci L; Fohner AE; Fornage M; Fox C; Franco OH; Galesloot TE; Garland T; Gieger C; Gordon SD; Graff M; Grarup N; Gudnason V; Gyllensten U; Hall LM; Haller T; Hansen T; Hartman CA; Hartwig FP; Hayward C; Heard-Costa N; Heiss G; Hemerich D; Hevener AL; Hillis DA; Holzapfel C; Horta BL; Hui J; Huikari V; Hypponen E; Illig T; Jackson AU; Jago R; James A; Jarvelin MR; Johansson A; Johnson WC; Jorgensen AM; Joshi PK; Jung T; Kaakinen MA; Kahonen M; Kardia SLR; Karlsson R; Kasbohm E; Kerr KF; Kiemeney LA; Kilpelainen TO; Kim B; Koh WP; Kolcic I; Koolhaas CM; Kraft PP; Krook A; Kutalik Z; Kuusisto J; Laakso M; Lagou V; Langenberg C; Launer LJ; Le Marchand L; Lehtimaki T; Li AH; Lind PA; Linneberg A; Liu CT; Loos RJF; Lorentzon M; Luan JA; Lyytikainen LP; Magnusson PKE; Mangino M; Martin NG; Mazzaferro E; Medland SE; Melbye M; Metspalu A; Metzendorf C; Meyre D; Milaneschi Y; Monroe KR; Moore T; Moscati A; Musk B; Nelson CP; Nolte IM; North KE; Ohlsson C; Oldehinkel AJ; Orho-Melander M; Pacolet A; Pare G; Park T; Pedersen NL; Pedersen O; Penninx BWJH; Pers TH; Perusse L; Peters A; Peyser PA; Pillon NJ; Polasek O; Pool R; Power C; Prokopenko I; Raitakari OT; Reedik M; Reiner AP; Richmond RC; Ridker PM; Rivera NV; Robiou-Du-Pont S; Rotimi CN; Rudan I; Ryan K; Samani NJ; Sarzynski MA; Schraut KE; Schulz CA; Scott LJ; Scott RA; Sidney S; Siggeirsdottir K; Sim X; Smith AV; Smith GD; Smith JA; Snieder H; Sonestedt E; Sorensen TIA; Spector TD; Stringham HM; Strom M; Tai ES; Tanaka T; Teo KK; Teumer A; Thomis MAI; Thorand B; Timpson NJ; Tonjes A; Tremblay A; Turman C; Uitterlinden AG; Van Dam RM; Van Duijn CM; Van Rooij FJA; Van Schoor N; Van Vliet-Ostaptchouk JV; Van der Most PJ; Van der Velde N; Vangipurapu J; Vanmunster M; Vidal PM; Volker U; Vollenweider P; Volzke H; Voortman T; Waeber G; Wang Z; Wareham NJ; Weir DR; Wichmann HE; Willemsen G; Williams K; Wilson JF; Wong Q; Xu HC; Young KL; Yuan JM; Zhang XS; Zhao JH; Zhao W; Zierath JR; Zillikens MC; Zonderman AB
Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in a multi-ancestry ...