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<p></p><p><br /></p><p></p><p>This study aimed to evaluate certain physical properties including surface wear of a new experimental short fiber-reinforced flowable resin composite (SFRC) in comparison with different commercial flowable bulk fill resin composites (SDR, Tetric EvoFlow Bulk Fill, Filtek Bulk Fill Flowable and Estelite Bulk Fill Flow). The following properties were examined according to ISO standard: flexural strength, flexural modulus, fracture toughness, water sorption, volumetric shrinkage, and depth of cure. Degree of conversion (DC%) was determined by FTIR spectrometry. A wear test was conducted with 15000 chewing cycles using a dual-axis chewing simulator. Wear depth was measured by a three-dimensional (3D) noncontact optical profilometer. Scanning electron microscopy was used to evaluate the microstructure of SFRC. Data were statistically analyzed with analysis of variance ANOVA (p = 0.05). SFRC exhibited the highest fracture toughness (2.8 MPa m1/2) and flexural strength (146.5 MPa) values (p < 0.05) and the greatest depth of cure (5 mm) and lowest wear depth (18.2 µm) among the flowable bulk fill materials tested. SDR showed the lowest volumetric shrinkage percentage (2.9%), while the other resin composites had comparable volumetric shrinkage values (p > 0.05). The new short fiber-reinforced flowable resin composite differed significantly in its measured fracture toughness compared to the tested flowable bulk fill resin composites.</p><p> </p><p><br /></p>...

<p>Purpose This study reviews our experience with deep neck space infections (DNIs) requiring surgical intervention, includingcervical necrotizing fasciitis. The aim of the study was to identify predisposing and aggravating ...

<p>This article will provide a brief overview of the methods in finding barriers and enablers in doing oral health research in India. This mixed-methods approach can be used by researchers in finding barriers and enablers ...

Objective: The aim of root canal obturation is to prevent leakage and inhibit microbial invasion. This study aimed to determine the effect of chlorhexidine (CHX) and dimethyl sulfoxide (DMSO) as final irrigants on microleakage ...

<p> Neurofibromatosis type 1 (NF1) is a common, hereditary, neurocutaneous skeletal condition with a variety of osseous manifestations. Although NF1 also affects craniofacial structures, the literature has only limited ...

This study aims to assess the efficacy of a universal adhesive (Scotchbond Universal, 3M ESPE) (SB) in total-etch mode, compared to a traditional orthodontic primer (Transbond XT Primer, 3M ESPE) (XT Primer), to perform ...

Consumer 3D printers have improved considerably due to the evolution of additive manufacturing. This study aimed to examine the accuracy of consumer printers in dental restoration. Cylindrical patterns mimicking a full ...

The objective of this retrospective study was to explore possible changes in histopathological features and expression of cyclin D1 and MIB-1 in salivary gland pleomorphic adenoma (PA) that recur or undergo malignant ...

<p>Simple Summary<br></p><p>Oropharyngeal squamous cell carcinoma (OPSCC) is a form of head and neck cancer in which human papillomavirus (HPV) infection has been shown to play a major role in disease development. The survival rates of HPV-positive patients are favorable compared to HPV-negative patients, but the reason for this phenomenon remains unclear. The management of OPSCC is complex, and development of novel treatment options is urgently required. Various possible factors affecting survival have been explored, including the tumor environment and cancer-related proteases. Our aim was to study a protease inhibitor known as tumor-associated trypsin inhibitor and its correlation with survival and clinical data in OPSCC patients.<br></p><p>Background: We studied the role of tumor-associated trypsin inhibitor (TATI) in serum and in tumor tissues among human papillomavirus (HPV)-positive and HPV-negative OPSCC patients. <br></p><p>Materials and methods: The study cohort included 90 OPSCC patients treated at the Helsinki University Hospital (HUS), Helsinki, Finland, in 2012-2016. TATI serum concentrations (S-TATIs) were determined by an immunofluorometric assay. Immunostaining was used to assess tissue expression. HPV status was determined with a combination of p16 immunohistochemistry and HPV DNA PCR genotyping. The survival endpoints were overall survival (OS) and disease-specific survival (DSS). <br></p><p>Results: A significant correlation was found between S-TATI positivity and poor OS (p < 0.001) and DSS (p = 0.04) in all patients. In HPV-negative cases, S-TATI positivity was linked to poor OS (p = 0.01) and DSS (p = 0.05). In HPV-positive disease, S-TATI positivity correlated with poor DSS (p = 0.01). S-TATI positivity was strongly associated with HPV negativity. TATI serum was negatively linked to a lower cancer stage. TATI expression in peritumoral lymphocytes was associated with favorable OS (p < 0.025) and HPV positivity. TATI expression in tumor and in peritumoral lymphocytes correlated with lower cancer stages. <br></p><p>Conclusion: Our results suggest that S-TATI positivity may be a biomarker of poor prognosis in both HPV-positive and HPV-negative OPSCC.</p>...