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Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the US

Frohnert Brigitte I.; Veijola Riitta; Killian Michael B.; Ghalwash Mohamed; Toppari Jorma; Winkler Christiane; Jonsson Josefine; Ng Kenney; Ziegler Anette-Gabriele; Lundgren Markus; Hagopian William; Koski Eileen; Dunne Jessica L.; Knip Mikael; Anand Vibha; Rewers Marian; for the T1DI Study Group; Ilonen Jorma; Liu Bin; Li Ying

<div><p>OBJECTIVE</p><p>To combine prospective cohort studies, by including HLA harmonization, and estimate risk of islet autoimmunity and progression to clinical diabetes.<br></p><p>RESEARCH DESIGN AND METHODS<br></p><p>For ...

Simulating Screening for Risk of Childhood Diabetes: The Collaborative Open Outcomes tooL (COOL)

Hagopian William; Anand Vibha; Koski Eileen; Rewers Mariam; Ghalwash Mohamed; Toppari Jorma; Veijola Riitta

<p>The Collaborative Open Outcomes tooL (COOL) is a novel, highly configurable application to simulate, evaluate and compare potential population-level screening schedules. Its first application is type 1 diabetes (T1D) ...