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Renal hemodynamics and fatty acid uptake: effects of obesity and weight loss
Human studies of renal hemodynamics and metabolism in obesity are insufficient. We hypothesized that renal perfusion and renal free fatty acid (FFA) uptake are higher in subjects with morbid obesity compared with lean ...
MR signal-fat-fraction analysis and T2*weighted imaging measure BAT reliably on humans without cold exposure
Objective. Brown adipose tissue (BAT) is compositionally distinct from white adipose tissue (WAT) in terms of triglyceride and water content. In adult humans, the most significant BAT depot is localized in the supraclavicular ...
Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity
<p>atty acids (FA) are important substrates for brown adipose tissue (BAT)
metabolism, however, it remains unclear whether there exists a
difference in FA metabolism of BAT between lean and obese healthy
humans. In ...
Let-7i-5p represses brite adipocyte function in mice and humans
In response to cold or beta 3-adrenoreceptor stimulation brown adipose tissue (BAT) promotes non-shivering thermogenesis, leading to energy dissipation. BAT has long been thought to be absent or scarce in adult humans. The ...