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Multimodality imaging: Bird's eye view from The European Society of Cardiology Congress 2017, Barcelona, August 26-30, 2017
<p>This year 2017, 396 imaging abstracts (43% of abstracts submitted under the topic of imaging) were presented at the European Society of Cardiology (ESC) congress, held in Barcelona from August 26th to 30th. For this ...
Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with F-18-GE-180, a Radiotracer for Translocator Protein (TSPO)
Intraplaque inflammation plays an important role in the progression of atherosclerosis.) The 18 kDa translocator protein (TSPO) expression is upregulated in activated macrophages, representing a potential target to identify ...
Myocardial tissue and metabolism characterization in men with alcohol consumption by cardiovascular magnetic resonance and 11C-acetate PET/CT
<div>Background: Chronic alcohol consumption initially leads to asymptomatic left ventricular dysfunction, but can result in myocardial impairment and heart failure if ongoing. This study sought to characterize myocardial ...
68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model
<p>Background<br />Magnetic resonance imaging (MRI) with Gadolinium 1,4,7,10-tetraazacyclododecane-N′,N″,N′′′,N″″-tetraacetic acid (Gd-DOTA) enables assessment of myocardial perfusion during first-pass of the contrast ...
Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
Background Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in ...
Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular 18F-FDG Uptake in Atherosclerotic Mice
<p>This study showed that treatment with a therapeutic monoclonal immunoglobulin-G1 antibody against phosphorylcholine on oxidized phospholipids preserves coronary flow reserve and attenuates atherosclerotic inflammation ...
Assessment of myocardial viability with [15O]water PET: A validation study in experimental myocardial infarction
<p>Background: Assessment of myocardial viability is often needed in patients with chest pain and reduced ejection fraction. We evaluated the performance of reduced resting MBF, perfusable tissue fraction (PTF), and ...
Variability of radiation doses of cardiac diagnostic imaging tests: the RADIO-EVINCI study (RADIationdOse subproject of the EVINCI study)
Background: Patients with coronary artery disease can accumulate significant radiation dose through repeated exposures to coronary computed tomographic angiography, myocardial perfusion imaging with single photon emission ...
Imaging in ESC clinical guidelines: Chronic coronary syndromes
<p>The European Society of Cardiology (ESC) has recently published new guidelines on the diagnosis and management of chronic coronary syndromes (CCS). The 2019 guideline identified six common clinical scenarios of CCS ...
[F-18]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs
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We found increased uptake of [F-18]FDG in coronary atherosclerotic lesions in a pig model. However, uptake in these early stage lesions was not detectable with in vivo PET imaging. Further studies are needed to clarify ...