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Seasonal variation in the brain μ-opioid receptor availability
<p>Seasonal rhythms influence emotion and sociability. The brain μ-opioid receptor (MOR) system modulates a multitude of seasonally varying socioemotional functions, but its seasonal variation remains elusive with no ...
Gut Microbiota Composition in Mid-Pregnancy Is Associated with Gestational Weight Gain but Not Prepregnancy Body Mass Index
<p>Background: Pregnancy is a time of numerous hormonal, metabolic, and immunological changes for both the mother and the fetus. Furthermore, maternal gut microbiota composition (GMC) is altered during pregnancy. One major ...
Resting-state networks of the neonate brain identified using independent component analysis
Resting-state functional magnetic resonance imaging (rs-fMRI) has been successfully used to probe the intrinsic functional organization of the brain and to study brain development. Here, we implemented a combination of ...
Sex-specific association between infant caudate volumes and a polygenic risk score for major depressive disorder
Polygenic risk scores for major depressive disorder (PRS-MDD) have been identified in large genome-wide association studies, and recent findings suggest that PRS-MDD might interact with environmental risk factors to shape ...
PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins
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Background:
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The PIM family kinases promote cancer cell survival and motility
as well as metastatic growth in various types of cancer. We have ...
Associations of age and sex with brain volumes and asymmetry in 2–5-week-old infants
<p>Information on normal brain structure and development facilitates the recognition of abnormal developmental trajectories and thus needs to be studied in more detail. We imaged 68 healthy infants aged 2–5 weeks with ...
Newborn amygdalar volumes are associated with maternal prenatal psychological distress in a sex-dependent way
<p>Maternal psychological distress during pregnancy (PPD)<a href="https://www.sciencedirect.com/science/article/pii/S2213158220302175#fn1">1</a> has been associated with changes in offspring amygdalar and hippocampal ...
Evaluation of [68Ga]Ga-DOTA-TCTP-1 for the Detection of Metalloproteinase 2/9 Expression in Mouse Atherosclerotic Plaques
Background: The expression of matrix metalloproteinases 2/9 (MMP-2/9) has been implicated in arterial remodeling and inflammation in atherosclerosis. We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 ...
Infant and Child MRI: A Review of Scanning Procedures
Magnetic resonance imaging (MRI) is a safe method to examine human brain. However, a typical MR scan is very sensitive to motion, and it requires the subject to lie still during the acquisition, which is a major challenge ...
Maternal pre-pregnancy BMI associates with neonate local and distal functional connectivity of the left superior frontal gyrus
Maternal obesity/overweight during pregnancy has reached epidemic proportions and has been linked with adverse outcomes for the offspring, including cognitive impairment and increased risk for neuropsychiatric disorders. ...