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Spontaneous preterm delivery is reflected in both early neonatal and maternal gut microbiota
<p>Abstract</p><p>Background<br>Aberrant gut microbiota composition in preterm neonates is linked to adverse health consequences. Little is known about the impact of perinatal factors or maternal gut microbiota on initial ...
Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial
<p>Background<br />The efficacy and safety of antibiotic treatment for uncomplicated acute appendicitis has<br />been established at long-term follow-up with the majority of recurrences shown to occur<br />within the first ...
The Effect of Consumer-based Activity Tracker Intervention on Physical Activity among Recent Retirees-An RCT Study
Purpose The randomized controlled trial REACT (NCT03320746) examined the effect of a 12-month consumer-based activity tracker intervention on accelerometer-measured physical activity among recent retirees. Methods Altogether ...
One-session cognitive behavior treatment for long-term frequent attenders in primary care: randomized controlled trial
<div>Aim: The aim of the study was to find out, if a single cognitive behavior treatment (CBT) session for long-term frequent attenders in primary care affects the attendance frequency and mental well-being of the patients. ...
Effects of school-based mindfulness intervention on health-related quality of life: moderating effect of gender, grade, and independent practice in cluster randomized controlled trial
<p><strong>Object</strong> <br></p><p>We investigated the impact of a school-based 9-week mindfulness program vs. active control program (relaxation) and inactive control group on children's self-reported Health-Related Quality of Life (HRQoL) moderated by gender, grade, and independent practice. <br></p><p><strong>Method</strong> <br></p><p>In total 3519 (50/50% boys/girls) Finnish students aged 12-15 years from 56 schools were randomized into mindfulness intervention, active, and inactive control groups. HRQoL was measured at baseline, at 9 weeks, and at 26 weeks and analyzed with multilevel linear modeling. <br></p><p><strong>Results</strong> <br></p><p>Significant improvement on HRQoL was found (β = mean difference) (β = 1.587, 95% CI 0.672-2.502, p < 0.001) after 9 weeks and at 26 weeks of follow-up among students in the mindfulness group as compared to the active control group. Moderating effects on HRQoL were found for gender, grade, and independent practice: girls, 7th and 8th grade students, and students with regular independent mindfulness practice benefited most. <br></p><p><strong>Conclusions</strong> <br></p><p>Gender and developmental stage may moderate the effects of mindfulness interventions on HRQoL and offer guidance in designing effective promotive interventions for children and adolescents.</p>...
Healthy Learning Mind (HLM): Cluster Randomized Controlled Trial on A Mindfulness Intervention, Moderators and Association with Perceived Socioeconomic Status, and Comparison to Other National Data
<p>Background <br></p><p>This paper presents the baseline characteristics and their moderators in the Healthy Learning Mind (HLM)- school-based cluster-randomized controlled trial. <br></p><p>Objectives <br></p><p>The paper ...
Readmissions due to hyperemesis gravidarum: a nation-wide Finnish register study
<p><strong>Purpose: </strong>To evaluate the burden of illness caused by hyperemesis gravidarum (HG) and association of readmissions due to HG with maternal, environmental and pregnancy-related factors, and different ...
Trends in the surgical management of vesicoureteral reflux in Finland in 2004-2014
<p>Objectives: Previous data on the trends of surgical treatment of vesicoureteral reflux outside USA are<br />scarce. The aim of this study was to clarify the national trends of operative treatment of vesicoureteral<br ...
Pilot Study on Students' Stress Reactivity After Mindfulness Intervention Compared to Relaxation Control Group
<p>The current pilot study examines the effects of a mindfulness intervention versus relaxation-based active control on psychophysiological reactivity measured by heart rate (HR), high-frequency heart rate variability ...
Sleep quality in women with nausea and vomiting of pregnancy: a cross-sectional study
BackgroundNausea and vomiting of pregnancy (NVP) deteriorates many aspects of daily lives of women. However, little is known about associations between NVP and sleep quality.MethodsWomen attending to routine mid-pregnancy ...