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Spontaneous preterm delivery is reflected in both early neonatal and maternal gut microbiota
<p>Abstract</p><p>Background<br>Aberrant gut microbiota composition in preterm neonates is linked to adverse health consequences. Little is known about the impact of perinatal factors or maternal gut microbiota on initial ...
Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females
Clinical presentations of mutations in the IQSEC2 gene on the X-chromosome initially implicated to cause non-syndromic intellectual disability (ID) in males have expanded to include early onset seizures in males as well ...
Trends in the surgical management of vesicoureteral reflux in Finland in 2004-2014
<p>Objectives: Previous data on the trends of surgical treatment of vesicoureteral reflux outside USA are<br />scarce. The aim of this study was to clarify the national trends of operative treatment of vesicoureteral<br ...
Sexually Dimorphic Associations between Maternal Factors and Human Milk Hormonal Concentrations
While human milk composition is characterised by marked dynamicity, we are far from having a clear picture of what factors drive this variation. Hormones in human milk are known to vary according to specific maternal ...
Attainment of Targets of the 20-Year Infancy-Onset Dietary Intervention and Blood Pressure Across Childhood and Young Adulthood The Special Turku Coronary Risk Factor Intervention Project (STRIP)
We examined whether success in achieving the key targets of an infancy-onset 20-year dietary intervention was associated with blood pressure (BP) from infancy to young adulthood. In the prospective randomized STRIP (Special ...
Growth Factor Concentrations in Human Milk Are Associated With Infant Weight and BMI From Birth to 5 Years
Background:Human milk bioactives may play a role in infant health and development. Although the variability in their concentrations in milk is well-established, the impact of differential milk profiles on infant growth ...
Intellectual disability in patients with epilepsy with eyelid myoclonias
We describe here the clinical outcome of four women with epilepsy with eyelid myoclonia (aged 21-53years). All patients had an uneventful early history, normal physical growth and appearance and no comorbid sensory or motor ...
Preterm children's developmental coordination disorder, cognition and quality of life: a prospective cohort study
<div><p><strong>Objective</strong> To evaluate the rate of developmental coordination disorder (DCD) and its correlation to cognition and self-experienced health-related quality of life (HRQoL) in children born very ...
Long-term changes in the incidence of childhood epilepsy. A population study from Finland
<h4>Background<br />The incidence of childhood epilepsy has changed during the past decades, but it is unclear whether it increased or decreased.</h4><h4>Methods<br />Changes in drug-treated childhood epilepsy between 1968 ...
An Infancy-Onset 20-Year Dietary Counselling Intervention and Gut Microbiota Composition in Adulthood
The randomized controlled Special Turku Coronary Risk Factor Intervention Project (STRIP) has completed a 20-year infancy-onset dietary counselling intervention to reduce exposure to atherosclerotic cardiovascular disease ...