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Spontaneous preterm delivery is reflected in both early neonatal and maternal gut microbiota
<p>Abstract</p><p>Background<br>Aberrant gut microbiota composition in preterm neonates is linked to adverse health consequences. Little is known about the impact of perinatal factors or maternal gut microbiota on initial ...
Effect of 12-month intervention with lipid-based nutrient supplement on the physical activity of Malawian toddlers: a randomised, controlled trial
<p>Physical activity is beneficial for children’s well-being. The effect of dietary supplementation on children’s physical activity in food-insecure areas remains little studied. We examined the effects of a lipid-based ...
Long-Term Outcomes of Surgical Aortic Valve Replacement in Patients with Rheumatoid Arthritis
Background: Patients with rheumatoid arthritis (RA) have increased risk of developing cardiovascular disease and events. Little is, however, known about the influence of RA to the outcomes after surgical aortic valve ...
Association of changes in lifestyle with changes in sleep difficulties: an analysis of 38 400 participants over a 16-year follow-up
<p><strong>Objectives</strong> To investigate the association between changes in lifestyle risk factors and changes is sleep difficulties. <br></p><p><strong>Design</strong> Longitudinal repeated measures cohort study. ...
Brain volumes in relation to loneliness and social competence in preadolescents born very preterm
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<h3> Introduction</h3>
<p>The aim of the present study was to assess how
regional brain volumes associate ...
Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial
<p>Background<br />The efficacy and safety of antibiotic treatment for uncomplicated acute appendicitis has<br />been established at long-term follow-up with the majority of recurrences shown to occur<br />within the first ...
Thigh-worn accelerometry for measuring movement and posture across the 24-hour cycle: a scoping review and expert statement
<p><strong>Introduction: </strong>The Prospective Physical Activity Sitting and Sleep consortium (ProPASS) is an international collaboration platform committed to harmonise thigh-worn accelerometry data. The aim of this ...
Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females
Clinical presentations of mutations in the IQSEC2 gene on the X-chromosome initially implicated to cause non-syndromic intellectual disability (ID) in males have expanded to include early onset seizures in males as well ...
Adiposity Markers as Predictors of 11-Year Decline in Maximal Walking Speed in Late Midlife
Background: Obesity is linked to poorer physical functioning in older adults, but impact of excess adiposity on loss of functional capacity in late midlife is unclear. This study examined associations between adiposity ...
Why do men extend their employment beyond pensionable age more often than women? a cohort study
Men extend their employment beyond pensionable age more often than women, but the factors that contribute to this sex difference are unknown. This study aimed to examine sex differences in extending employment and the ...