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A Miniaturized MEMS Motion Processing System for Nuclear Medicine Imaging Applications
<p>Cardiac, respiratory, and patient body motion artifacts
degrade the image quality and quantitative accuracy of
the nuclear medicine imaging which may lead to incorrect
diagnosis, unnecessary treatment and insufficient ...
Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with F-18-GE-180, a Radiotracer for Translocator Protein (TSPO)
Intraplaque inflammation plays an important role in the progression of atherosclerosis.) The 18 kDa translocator protein (TSPO) expression is upregulated in activated macrophages, representing a potential target to identify ...
Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation
BackgroundPositron emission tomography (PET) can be used for in vivo evaluation of the pathology associated with multiple sclerosis. We investigated the use of longitudinal PET imaging and the 18-kDa translocator protein ...
Brain volumes in relation to loneliness and social competence in preadolescents born very preterm
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<h3> Introduction</h3>
<p>The aim of the present study was to assess how
regional brain volumes associate ...
Positron emission tomography imaging in evaluation of MS pathology in vivo
<p>Positron emission tomography (PET) gives an opportunity to quantitate
the expression of specific molecular targets in vivo and longitudinally
in brain and thus enhances our possibilities to understand and follow ...
68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model
<p>Background<br />Magnetic resonance imaging (MRI) with Gadolinium 1,4,7,10-tetraazacyclododecane-N′,N″,N′′′,N″″-tetraacetic acid (Gd-DOTA) enables assessment of myocardial perfusion during first-pass of the contrast ...
Brain structural alterations in autism and criminal psychopathy
The goal of this study was to elucidate the anatomical brain basis of social cognition through two disorders with distinctively different phenotypes of social interaction. We compared structural MR images of 20 individuals ...
First-in-Human Study of 68 Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1
Sialic acid-binding immunoglubulin-like lectin 9 (Siglec-9) is a ligand of vascular adhesion protein 1 (VAP-1). A gallium 68-labeled peptide of Siglec-9, <sup>68</sup>Ga-DOTA-Siglec-9, holds promise as a novel PET tracer ...
Seasonal variation in the brain μ-opioid receptor availability
<p>Seasonal rhythms influence emotion and sociability. The brain μ-opioid receptor (MOR) system modulates a multitude of seasonally varying socioemotional functions, but its seasonal variation remains elusive with no ...
Prognostic imaging biomarkers for diabetic kidney disease (iBEAt): study protocol
<b>Background:</b> Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) ...