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Granulocyte colony-stimulating factor- and chemotherapy-induced large-vessel vasculitis: six patient cases and a systematic literature review
<div>Patients receiving chemotherapy are prone to neutropoenic infections, presenting with non-specific symptoms such as a high fever and elevated inflammatory parameters. Large-vessel vasculitis (LVV) may have a similar ...
Biomarkers of kidney function and prediction of death from cardiovascular and other causes in the elderly: A 9-year follow-up study
Background: Cystatin C is claimed to be superior to creatinine-based estimates of glomerular filtration rate (eGFRcr). The purpose of the study is to analyze whether cystatin C, creatinine, and/or estimated glomerular ...
Tonsillar transcriptional profiles in atopic and non-atopic subjects
<p>Background <br></p><p>Emerging research suggests that local lymphatic tissue such as tonsils have important role in regulating the immune responses. However, allergen sensitization-induced alterations in transcriptome ...
Atopic asthma after rhinovirus-induced wheezing is associated with DNA methylation change in the SMAD3 gene promoter
<p>Children with rhinovirus-induced severe early wheezing have an increased risk of developing asthma later in life. The exact molecular mechanisms for this association are still mostly unknown. To identify potential changes ...
Sarjamagneettistimulaatio kivun ja neurologisten sairauksien hoidossa
<p>• Aivojen sarjamagneettistimulaatio (rTMS) on kajoamaton neuromodulaatiohoito, jolla ei ole turvasuosituksia noudatettaessa vakavia haittavaikutuksia.</p><p>• Eurooppalaisessa näytönastekatsauksessa rTMS on arvioitu ...
Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target
BackgroundReceptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or ...
Validating 10-joint juvenile arthritis disease activity score cut-offs for disease activity levels in non-systemic juvenile idiopathic arthritis
<div><p><strong>Objectives</strong>
To validate cut-offs of the Juvenile Arthritis Disease Activity Score
10 (JADAS10) and clinical JADAS10 (cJADAS10) and to compare them with
other patient cohorts.</p></div><div>< ...
Breast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors
<div><h3>Abstract</h3><div><h4>BACKGROUND: </h4><p>An increased breast cancer incidence and poor survival have been reported for women with neurofibromatosis 1 (NF1). To explain the poor survival, we aimed to link the ...