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Effects of short-term sprint interval and moderate-intensity continuous training on liver fat content, lipoprotein profile, and substrate uptake: a randomized trial

Nina Savisto; Kumail K. Motiani; Minna Yli-Karjanmaa; Jarna C. Hannukainen; Olof Solin; Virva Saunavaara; Merja Haaparanta-Solin; Jussi Toivanen; Juhani Knuuti; Eliisa Löyttyniemi; Jari-Joonas Eskelinen; Kari K. Kalliokoski; Riitta Parkkola; Kirsi A. Virtanen; Anna M. Savolainen; Pirjo Nuutila; Marja A. Heiskanen

<div>Type 2 diabetes (T2D) and increased liver fat content (LFC) alter lipoprotein profile and composition and impair liver substrate uptake. Exercise training mitigates T2D and reduces LFC, but the benefits of different ...

[F-18]FMPEP-d(2) PET imaging shows age- and genotype-dependent impairments in the availability of cannabinoid receptor 1 in a mouse model of Alzheimer's disease

Anniina Snellman; Merja Haaparanta-Solin; Jatta S. Takkinen; Olof Solin; Rea Pihlaja; Francisco R. López-Picón; Juha O. Rinne; Anna K. Kirjavainen; Eliisa Löyttyniemi; Tamiko Ishizu

Contradictory findings on the role of the type 1 cannabinoid receptor (CB1R) during the pathogenesis of Alzheimer's disease (AD) have been reported. Here, we evaluated the CB1R brain profile in an AD mouse model using ...