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Aineistot 11-20 / 78
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the US
<div><p>OBJECTIVE</p><p>To combine prospective cohort studies, by including HLA harmonization, and estimate risk of islet autoimmunity and progression to clinical diabetes.<br></p><p>RESEARCH DESIGN AND METHODS<br></p><p>For ...
Children's erythrocyte fatty acids are associated with the risk of islet autoimmunity
Our aim was to investigate the associations between erythrocyte fatty acids and the risk of islet autoimmunity in children. The Environmental Determinants of Diabetes in theYoung Study (TEDDY) is a longitudinal cohort study ...
Attainment of Targets of the 20-Year Infancy-Onset Dietary Intervention and Blood Pressure Across Childhood and Young Adulthood The Special Turku Coronary Risk Factor Intervention Project (STRIP)
We examined whether success in achieving the key targets of an infancy-onset 20-year dietary intervention was associated with blood pressure (BP) from infancy to young adulthood. In the prospective randomized STRIP (Special ...
Infant and Child MRI: A Review of Scanning Procedures
Magnetic resonance imaging (MRI) is a safe method to examine human brain. However, a typical MR scan is very sensitive to motion, and it requires the subject to lie still during the acquisition, which is a major challenge ...
Extended spectrum penicillins reduce the risk of omphalocele: A population-based case-control study
<p><strong>Background: </strong>Omphalocele is a major congenital anomaly associated with significant morbidity and mortality. Regardless, the influence of maternal use of prescription drugs on the risk of omphalocele has ...
Maternal pre-pregnancy BMI associates with neonate local and distal functional connectivity of the left superior frontal gyrus
Maternal obesity/overweight during pregnancy has reached epidemic proportions and has been linked with adverse outcomes for the offspring, including cognitive impairment and increased risk for neuropsychiatric disorders. ...
Imputing Longitudinal Growth Data in International Pediatric Studies: Does CDC Reference Suffice?
This study investigates a missing value imputation approach for longitudinal growth data in pediatric studies from multiple countries. We analyzed a combined cohort from five natural history studies of type 1 diabetes (T1D) ...
Growth Factor Concentrations in Human Milk Are Associated With Infant Weight and BMI From Birth to 5 Years
Background:Human milk bioactives may play a role in infant health and development. Although the variability in their concentrations in milk is well-established, the impact of differential milk profiles on infant growth ...
Onset and progression of puberty in Klinefelter syndrome
<p><strong>Objective: </strong>Klinefelter syndrome (KS) (47,XXY and variants, KS) is the most common sex chromosome disorder in humans. However, little is known about the onset and progression of puberty in patients with ...
Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples
<p>DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, ...