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Aineistot 21-30 / 61
Impact of combined consumption of fish oil and probiotics on the serum metabolome in pregnant women with overweight or obesity
<p><strong>Background: </strong>If a pregnant woman is overweight, this can evoke metabolic alterations that may have health consequences for both mother and child.</p><p><strong>Methods: </strong>Pregnant women with ...
Frailty, walking ability and self-rated health in predicting institutionalization: an 18-year follow-up study among Finnish community-dwelling older people
<p>Background <br></p><p>In clinical practice, there is a need for an instrument to screen older people at risk of institutionalization. Aims To analyze the association of frailty, walking-ability and self-rated health (SRH) with institutionalization in Finnish community-dwelling older people. <br></p><p>Methods <br></p><p>In this prospective study with 10- and 18-year follow-ups, frailty was assessed using FRAIL Scale (FS) (n = 1087), Frailty Index (FI) (n = 1061) and PRISMA-7 (n = 1055). Walking ability was assessed as self-reported ability to walk 400 m (n = 1101). SRH was assessed by a question of general SRH (n = 1105). Cox regression model was used to analyze the association of the explanatory variables with institutionalization. <br></p><p>Results <br></p><p>The mean age of the participants was 73.0 (range 64.0-97.0) years. Prevalence of institutionalization was 40.8%. In unadjusted models, frailty was associated with a higher risk of institutionalization by FS in 10-year follow-up, and FI in both follow-ups. Associations by FI persisted after age- and gender-adjustments in both follow-ups. By PRISMA-7, frailty predicted a higher risk of institutionalization in both follow-ups. In unadjusted models, inability to walk 400 m predicted a higher risk of institutionalization in both follow-ups and after adjustments in 10-year follow-up. Poor SRH predicted a higher risk of institutionalization in unadjusted models in both follow-ups and after adjustments in 10-year follow-up. <br></p><p>Discussion <br></p><p>Simple self-reported items of walking ability and SRH seemed to be comparable with frailty indexes in predicting institutionalization among community-dwelling older people in 10-year follow-up. Conclusions In clinical practice, self-reported walking ability and SRH could be used to screen those at risk.</p>...
Prediagnostic expressions in health records predict mortality in Parkinson's disease: A proof-of-concept study
<p><br></p><p>Introduction: The relationship of prodromal markers of PD with PD mortality is unclear. Electronic health records (EHRs) provide a large source of raw data that could be useful in the identification of novel ...
Knowledge of patient observation among critical care nurses
<p>Background <br></p><p>The clinical observations made by critical care nurses are vital for maintaining patient safety and making appropriate decisions in the care of patients who are critically ill. Evaluating the ...
A therapist-guided smartphone app for major depression in young adults: A randomized clinical trial
<p>Background: Meru Health Program (MHP) is a therapist-guided, 8-week intervention for depression delivered via smartphone. The aim was to test its efficacy in patients with clinical depression in a Finnish university ...
Hypopharyngeal carcinoma in Finland from 2005 to 2014: outcome remains poor after major changes in treatment
<p>Purpose <br></p><p>Hypopharyngeal carcinoma (HPC) is typically diagnosed at late stages, the patients tend to have serious co-morbidities, distant relapses are frequent, and the related mortality remains high. The ...
Iodine status in pregnant women and infants in Finland
<p><strong>Purpose: </strong>Iodine insufficiency during pregnancy may adversely influence fetal growth and development. There is a lack of information on iodine status in pregnant women and infants in many countries ...
Foundations of human consciousness: Imaging the twilight zone
<p>What happens in the brain when conscious awareness of the surrounding world fades? We manipulated consciousness in two experiments in a group of healthy males and measured brain activity with positron emission tomography. ...
An Evidence-Based Educational Intervention for Reducing Coercive Measures in Psychiatric Hospitals: A Randomized Clinical Trial
<p>Importance <br>Investing in health care staffs’ education can change the scope of action and improve care. The effectiveness of staff education remains inconclusive.</p><p>Objective <br>To examine whether an evidence-based ...
Monthly variation in univentricular heart and transposition of the great arteries-10-year national population-based cohort study
Objective: Monthly variation in the total prevalence of the univentricular heart (UVH) and dextro-transposition of the great arteries (d-TGA) at gestational age 7 + 0 weeks was assessed to determine potential environmental ...