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Clinical trial site identification practices and the use of electronic health records in feasibility evaluations: An interview study in the Nordic countries
<p><strong>Introduction: </strong>Feasibility evaluations are performed to create the best possible starting point for the set-up and execution of a clinical trial, and to identify any obstacles for successful trial conduct. ...
Kouluhyvinvointi syntyy vain yhteistyöllä
<p>Lapsi- ja perhepalveluiden muutosohjelman (LAPE) mukaan hyvinvoiva lapsi
oppii ja kasvaa. Edessä olevan kouluvuoden alussa onkin hyvä pysähtyä
miettimään mitä kouluhyvinvointi on ja miten voimme edistää sitä ...
IL-6 and other biomarkers as predictors of severity in COVID-19
<p>Objective<br></p><p>Cytokine release syndrome is suggested to be the most important mechanism triggering acute respiratory distress syndrome and end organ damage in COVID-19. The severity of disease may be measured by ...
Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases
Mitosis represents a clinically important determination point in the life cycle of proliferating cells. One potential drug target within the mitotic machinery is the spindle assembly checkpoint (SAC), an evolutionarily ...
Occlusal traits and orthodontic treatment need in 7- to 10-year-olds in Estonia
The aim of this study was to evaluate the distribution of occlusal traits and orthodontic treatment need and complexity in Estonian 7-to 10-year-old children. This data provides solid information for planning of orthodontic ...
Extralevator versus standard abdominoperineal excision in locally advanced rectal cancer: a retrospective study with long-term follow-up
To analyze the results of abdominoperineal excisions (APE) for locally advanced rectal cancer at our institution before and after the adoption of extralevator abdominoperineal excision (ELAPE) with a special reference to ...
18-kDa translocator protein ligand 18F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice
<p>18F-FEMPA shows rapid blood clearance and uptake in the mouse aorta. Uptake in atherosclerotic plaques correlated with the amount of macrophages, but did not exceed that in the normal vessel wall.<br /></p>