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Aineistot 81-89 / 89
Epigeneettinen periytyminen sukusolulinjassa
Ympäristön aiheuttamat muutokset geenien toiminnassa voivat periytyä sukupolvelta toiselle sukusolujen välityksellä ja vaikuttaa näin jälkikasvun fenotyyppiin, ilman että {DNA}:n emäsjärjestyksessä tapahtuu muutoksia. ...
Lapsen epäselvän sukupuolen diagnostiikka ja hoito
Kun vastasyntyneen sukupuolta ei pystytä heti tunnistamaan, häneltä tulee sulkea pois hengenvaarallinen lisämunuaisten vajaatoimintaan johtava virilisoiva lisämunuaishyperplasia ja tarvittaessa aloittaa siihen gluko- ja ...
Simulating Screening for Risk of Childhood Diabetes: The Collaborative Open Outcomes tooL (COOL)
<p>The Collaborative Open Outcomes tooL (COOL) is a novel, highly configurable application to simulate, evaluate and compare potential population-level screening schedules. Its first application is type 1 diabetes (T1D) ...
Gut Microbiota and Serum Metabolome in Elite Cross-Country Skiers: A Controlled Study
Exercise has been shown to affect gut the microbiome and metabolic health, with athletes typically displaying a higher microbial diversity. However, research on the gut microbiota and systemic metabolism in elite athletes ...
The efficacy of probiotics and/or n-3 long-chain polyunsaturated fatty acids intervention on maternal prenatal and postnatal depressive and anxiety symptoms among overweight and obese women
Maternal depression and anxiety may endanger well-being of both mother and child. We investigated the efficacy of probiotics and/or fish oil (FO) in modifying pre- and postnatal depressive and anxiety symptoms. Symptom ...
Pubarche and Gonadarche Onset and Progression Are Differently Associated With Birth Weight and Infancy Growth Patterns
<p>Context: Controversy exists regarding associations between early-life growth patterns and timing of puberty.<br></p><p>Objective: This work aims to investigate associations between birth anthropometry, early growth ...
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study
<p>Fungal infections are a major health problem that often begin in the gastrointestinal tract. Gut microbe interactions in early childhood are critical for proper immune responses, yet there is little known about the ...
Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations
<p>Background:<br>ChREBP (carbohydrate responsive element binding protein) is a transcription factor that responds to sugar consumption. Sugar-sweetened beverage (SSB) consumption and genetic variants in the CHREBP locus ...