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Dietary Intervention in Infancy and Cognitive Function in Young Adulthood: The Special Turku Coronary Risk Factor Intervention Project
<p><strong>Objective: </strong>Consumption of saturated fatty acids (SAFAs), polyunsaturated fatty acids (PUFAs), cholesterol, and fiber have been linked with cognitive function in adults. We evaluated these associations ...
Weight gain in infancy and markers of cardiometabolic health in young adulthood
Aim We studied whether repeatedly measured weight gain from birth up to age 2 years associated with cardiometabolic health in young adulthood. Methods Using the data collected in the longitudinal Special Turku Coronary ...
Long-Lasting T Cell Responses in BNT162b2 COVID-19 mRNA Vaccinees and COVID-19 Convalescent Patients
<p>The emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made it more difficult to prevent the virus from spreading despite available vaccines. Reports of breakthrough ...
Sydän- ja verisuonitautien ehkäisy kannattaa aloittaa jo vauvasta - STRIP-tutkimus näyttää miksi ja miten
Satunnaistetussa STRIP-tutkimuksessa 562 tervettä lasta sai tyydyttyneen rasvan saannin vähentämiseen tähtäävää ravitsemusneuvontaa kahdeksan kuukauden iästä alkaen 20 vuoden ikään asti, ja 545 saman ikäistä lasta seurattiin ...
An Infancy-Onset 20-Year Dietary Counselling Intervention and Gut Microbiota Composition in Adulthood
The randomized controlled Special Turku Coronary Risk Factor Intervention Project (STRIP) has completed a 20-year infancy-onset dietary counselling intervention to reduce exposure to atherosclerotic cardiovascular disease ...
A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts
<p><b>Introduction </b>Peptide markers of inflammation have been associated with the development of type 2 diabetes. The role of upstream, lipid-derived mediators of inflammation such as eicosanoids, remains less clear. ...
Renal Sinus Fat Is Expanded in Patients with Obesity and/or Hypertension and Reduced by Bariatric Surgery Associated with Hypertension Remission
Renal sinus fat is a fat depot at the renal hilum. Because of its location around the renal artery, vein, and lymphatic vessels, an expanded renal sinus fat mass may have hemodynamic and renal implications. We studied ...
Detection of group A streptococcus in children with confirmed viral pharyngitis and antiviral host response
<p>Our aim was to study the detection of group A streptococcus (GAS) with different diagnostic methods in paediatric pharyngitis patients with and without a confirmed viral infection. In this prospective observational ...
Obesity risk is associated with brain glucose uptake and insulin resistance
<p><strong>Objective: </strong>To investigate whether alterations in brain glucose uptake (BGU), insulin action in the brain-liver axis and whole-body insulin sensitivity occur in young adults in pre-obese state.</p><p>< ...
Effects of altered salt intake and diet on cytokines in humans: A 20-week randomized cross-over intervention study
High sodium concentration alters leukocyte activation, and in particular T-helper (Th) lymphocyte polarization, and drives the development of autoimmune diseases in mouse studies. Similar results have been obtained with ...