Hae

Aineistot 1-10 / 25

Childhood and long-term dietary calcium intake and adult cardiovascular risk in a population with high calcium intake

Lehtimäki Terho; Raitakari Olli T.; Hutri-Kähönen Nina; Jula Antti; Kähönen Mika; Viikari Jorma S.A.; Rovio Suvi P.; Pahkala Katja; Magnussen Costan G.; Laitinen Tomi; Smith Kylie J.; Sabin Matthew A.; Juonala Markus; Rönnemaa Tapani; Wu Feitong

Background & aimsThe influence of dietary calcium intake in childhood on adult cardiovascular health is unknown, particularly in those with long-term high intake. To examine both linear and non-linear associations ...

68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model

Heidi Liljenbäck; Vesa Oikonen; Juhani Knuuti; Max Kiugel; Sauli Uotila; Nobuyuki Kudomi; Ville Kytö; Semi Helin; Olli Metsälä; Anu Autio; Anne Roivainen; Antti Saraste

Background Magnetic resonance imaging (MRI) with Gadolinium 1,4,7,10-tetraazacyclododecane-N′,N″,N′′′,N″″-tetraacetic acid (Gd-DOTA) enables assessment of myocardial perfusion during first-pass of the contrast ...

Dietary Intervention in Infancy and Cognitive Function in Young Adulthood: The Special Turku Coronary Risk Factor Intervention Project

Jula Antti; Raitakari Olli T.; Niinikoski Harri; Viikari Jorma S.A.; Rönnemaa Tapani; Pahkala Katja; Lagström Hanna; Salo Pia; Salo Henri; Rovio Suvi P.

Objective: Consumption of saturated fatty acids (SAFAs), polyunsaturated fatty acids (PUFAs), cholesterol, and fiber have been linked with cognitive function in adults. We evaluated these associations ...

Weight gain in infancy and markers of cardiometabolic health in young adulthood

Pahkala Katja; Viikari Jorma; Salo Pia; Jula Antti; Rönnemaa Tapani; Nummela Saga R; Raitakari Olli T; Rovio Suvi P; Niinikoski Harri

Aim We studied whether repeatedly measured weight gain from birth up to age 2 years associated with cardiometabolic health in young adulthood. Methods Using the data collected in the longitudinal Special Turku Coronary ...

Attainment of Targets of the 20-Year Infancy-Onset Dietary Intervention and Blood Pressure Across Childhood and Young Adulthood The Special Turku Coronary Risk Factor Intervention Project (STRIP)

Jula Antti; Simell Olli; Viikari Jorma S.A.; Raitakari Olli T.; Lagström Hanna; Niinikoski Harri; Pahkala Katja; Jokinen Eero; Rovio Suvi P.; Magnussen Costan G.; Nuotio Joel; Laitinen Tomi T.; Juonala Markus; Sabin Matthew; Burgner David; Rönnemaa Tapani

We examined whether success in achieving the key targets of an infancy-onset 20-year dietary intervention was associated with blood pressure (BP) from infancy to young adulthood. In the prospective randomized STRIP (Special ...

Sydän- ja verisuonitautien ehkäisy kannattaa aloittaa jo vauvasta - STRIP-tutkimus näyttää miksi ja miten

Viikari Jorma; Niinikoski Harri; Laitinen Tomi T; Raitakari Olli; Jula Antti; Salo Pia; Rönnemaa Tapani; Jokinen Eero; Pahkala Katja; Lagström Hanna; Rovio Suvi

Satunnaistetussa STRIP-tutkimuksessa 562 tervettä lasta sai tyydyttyneen rasvan saannin vähentämiseen tähtäävää ravitsemusneuvontaa kahdeksan kuukauden iästä alkaen 20 vuoden ikään asti, ja 545 saman ikäistä lasta seurattiin ...

Assessment of myocardial viability with [15O]water PET: A validation study in experimental myocardial infarction

Tuula Tolvanen; Mikko Pietilä; Mark Lubberink; Tuomas Kiviniemi; Timo Savunen; Juhani Knuuti; Mika Teräs; Seppo Ylä-Herttuala; Antti Saraste; Jarmo Teuho; Miikka Tarkia; Antti Kuivanen; Maria Grönman; Virva Saunavaara; Paavo Halonen; Anne Roivainen; Christoffer Stark; Tommi Vähäsilta

Background: Assessment of myocardial viability is often needed in patients with chest pain and reduced ejection fraction. We evaluated the performance of reduced resting MBF, perfusable tissue fraction (PTF), and ...

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Zemel BS; Iniguez C; Pedersen O; Koletzko B; Escribano J; Monnereau C; Uitterlinden AG; Bisgaard H; Atalay M; Froguel P; Curtin JA; Chesi A; Sly PD; Zeggini E; Heude B; Geller F; Freathy RM; Pennell CE; Horikoshi M; Viikari J; Grote V; Yengo L; Lyytikainen LP; Kuhnapfel A; Korner A; Holm JC; Hakonarson H; Verduci E; Gruszfeld D; Reischl E; Teo KK; Lehtimaki T; Bilbao JR; Bacelis J; Rivadeneira F; Beaumont RN; Reijneveld SA; Johansson S; Vonk JM; Lakka TA; Jarvelin MR; Morgen CS; Timpson NJ; Schnurr TM; Plomin R; Kirsten H; Eriksson JG; Ahluwalia TS; Thiering E; Pahkala K; van der Most PJ; Felix JF; Grarup N; Farooqi IS; Standl M; Simpson A; Groen-Blokhuis M; Bustamante M; Hattersley AT; Barroso I; Njolstad PR; Medina-Gomez C; Sebert S; Charles MA; Hottenga JJ; Lindi V; Raitakari O; Melbye M; Brown CD; Stergiakouli E; Vrijheid M; van Beijsterveldt CEM; Bradfield JP; Boomsma DI; Sunyer J; Zafarmand MH; Vilor-Tejedor N; Hypponen E; Scholz M; Vogel M; Jaddoe VWV; Holt PG; Heinrich J; Landgraf K; Closa-Monasterolo R; Custovic A; Dedoussis GD; Li AHL; Rzehak P; Hansen T; Helgeland O; Lind MV; Vaudel M; Cousminer DL; Snieder H; Alyass A; Joro R; Vrijkotte TGM; Grant SFA; Ntalla I; van Schaik BDC; Meyre D; Lowry E; Michaelsen KF; Hollensted M; Have CT; Stokholm J; Smith GD; Heiskala A; Koppelman GH; Selzam S; Kiess W; McCarthy MI; Knight BA; Beilin LJ; Nohr EA; Jacobsson B; Wheeler E; Panoutsopoulou K; Clement K; Nielsen TRH; Carstensen L; Feenstra B; Niinikoski H; Karhunen V; Sorensen TIA; Frithioff-Bojsoe C; Wang CRA; Chawes B; Bonnelykke K; Kahonen M; Torrent M; Langhendries JP; Vogelezang S; Fedko IO; Leinonen JT; Vinding RK; Power C; Ong K; Mori TA; Widen E; Murray C; Santa-Marina L; Pitkanen N; Oldehinkel AJ

The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed ...

Low serum adiponectin levels in childhood and adolescence predict increased intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study

Laitinen Tomi; Taittonen Leena; Viikari Jorma S. A.; Jokinen Eero; Huupponen Risto; Juonala Markus; Hutri-Kähönen Nina; Raitakari Olli T.; Saarikoski Liisa A; Lehtimäki Terho

Introduction: Low adiponectin levels may predict the development of atherosclerosis. We examined the association of childhood adiponectin with preclinical carotid atherosclerosis that is defined as plaque and/or ...

Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

Kuivanen A; Saukko P; Halonen P; Teuho J; Tarkia M; Saraste A; Käkelä M; Metsälä O; Pietilä M; Tolvanen T; Grönman M; Knuuti J; Kiviniemi T; Savunen T; Ylä-Herttuala S; Roivainen A

BACKGROUND: Radiolabeled RGD peptides detect αvβ3 integrin expression associated with angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied whether cardiac positron emission ...