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Vimentin modulates focal adhesion dynamics in directionally migrating fibroblasts
(2018-10-19)
Cell migration is an integral process in several physiological events essential for normal functioning of an organism. Cell migration is a mechanistic phenomenon that occurs in many steps including cell polarization, ...
The ω subunit of the RNA polymerase and the Ssr1600 protein play roles in high CO2 acclimation of the cyanobacterium Synechocystis sp. PCC 6803
(2020-01-05)
The transcription machinery of cyanobacteria includes the RNA polymerase (RNAP) with core composition of α2ββ’γω. For transcription initiation, the RNAP core recruits one of the σ factors. The ω subunit of RNAP is non-essential ...
Harnessing Microbial Interactions to Elicit the Production of Polyene Macrolides in Streptomyces
(2018-12-11)
Since their discovery in the 1950s, polyene macrolides have been invaluable for treating life threatening fungal infections. Polyene antibiotics are unique because they target ergosterol, the fungal sterol, and disrupt the ...
Chlamydomonas reinhardtii, a green microalga capable of growing in very high light
(2019-05-21)
Plants, algae and cyanobacteria convert sunlight to chemical energy in the process of photosynthesis. Photosynthesis is, however, also damaged by light, mainly through photoinhibition of photosystem II (PSII), which is ...
Calcium-Induced Proteome Changes in Isolated Chloroplasts of Arabidopsis Thaliana
(Turun yliopisto, 2017-05-09)
Calcium is a well-known regulator of various biological processes, such as photosynthesis, resulting from responses to environmental cues that are recognized by specific calcium sensors, which give rise to intracellular ...
Light-induced oxidative damage in yellow-green algae Vaucheria litorea
(2018-09-21)
Sea slug Elysia chlorotica incorporates chloroplasts of yellow-green algae Vaucheria litorea into its digestive tract cells where the chloroplasts remain active up to 9 months. The mechanism how these incorporated chloroplasts, ...
MARCO expressing macrophages as a target of cancer immunotherapy
(2019-05-10)
Macrophage receptor with collagenous structure (MARCO) was previously found to be expressed on a subpopulation of pro-tumorigenic M2-type macrophages in different mouse and human tumors. Furthermore, targeting these MARCO+ ...
Localization of root-type ferredoxin-NADP+ oxidoreductases in Arabidopsis thaliana
(Turun yliopisto, 2017-09-18)
Arabidopsis thaliana (Arabidopsis) genome encodes four plant-type ferredoxin-NADP+ oxidoreductases (FNRs) that mainly function in photosynthesis and anabolic metabolism. The two leaf-type FNRs present in chloroplasts are ...
Potential of native microalgae strains grown in wastewater for biodiesel production in Nordic climate
(Turun yliopisto, 2016-09-20)
The potential advantages of microalgae as a biodiesel feedstock have been clearly proved in several studies from recent years. However, the next step towards industrial scale of biodiesel production remains still incomplete. ...
Do the secreted molecules of gut bacterium Faecalibacterium prausnitzii inhibit the fat accumulation in hepatocytes in vitro?
(Turun yliopisto, 2016-12-14)
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder in which fat accumulates in liver without excessive alcohol use. NAFLD is a disease in which distortions in gut microbiota seems to play an important role. ...