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PUUTIAISAIVOKUUMEVIRUKSEN RAKENNEPROTEIINIEN VAIKUTUS LUONTAISEN IMMUNITEETIN VASTEISIIN
(2018-10-17)
Puutiaisaivokuumevirus (engl. tick-borne encephalitis virus, TBEV) on puutiaisen välityksellä ihmiseen tarttuva virus, joka voi aiheuttaa jopa fataalin meningoenkefaliitin. TBEV flavivirus, ja sen perimä on muiden flavivirusten ...
Multiplex diagnostics : development of serological dualmode multiplex microarray immunoassay and analysis of influenza and respiratory syncytial virus disease burden in early childhood
(Turun yliopisto, 2019-12-13)
Respiratory syncytial virus (RSV) and influenza A (IAV) and B (IBV) viruses infect humans throughout their life with exceptionally high rates of re-infection. Serological assays are commonly used to diagnose and characterize ...
Treatment of herpes simplex virus infection using antiviral siRNA swarms with 2’-fluoro-modifications
(2020-04-28)
Herpes simplex virus 1 (HSV-1) is a very common pathogen. Besides mostly harmless oral lesions, HSV-1 causes severe diseases such as neonatal herpes, herpes encephalitis and herpes keratitis, the primary cause of infectious ...
Interaction of filovirus proteins with RIG-I signaling pathways
(Turun yliopisto, 2022-06-10)
Filovirus family consist of highly pathogenic negative-strand RNA viruses that are characterized by their filamentous virion structure. The main focus in previous research has been on ebolaviruses and marburgviruses due ...
Vanhusten hengitystieinfektioiden virusetiologia
(Turun yliopisto, 2016-02-08)
Influenssarokotteiden synnyttämä immuunisuoja
(2021-03-08)
Ortomyksoviruksiin kuuluvat influenssavirukset voidaan jakaa pintaproteiinien perusteella eri luokkiin, joista kausi-influenssaa aiheuttavat A- ja B-tyypin virukset. Influenssaviruksen aiheuttama infektio on varsinkin ...
Antiviral modified siRNA swarms for treatment of herpes simplex virus infection
(Turun yliopisto, 2023-03-17)
Herpes simplex virus type 1 (HSV-1) is a common virus of humans carried by half of the global population. After the primary infection, HSV has the ability to establish life-long latency, wherefrom it can reactivate. The ...
Influenza vaccine induced antibody responses in relation to evolution of influenza A viruses
(Turun yliopisto, 2022-12-09)
Influenza A viruses (IAVs) cause yearly epidemics and occasionally appearing new pandemics. IAVs are subtyped based on their virion surface glycoproteins haemagglutinin and neuraminidase. Seasonal IA epidemics in humans ...
Bioinformatics of human picornavirus molecular evolution and pathogenesis
(Turun yliopisto, 2022-12-16)
Picornaviruses are a family of small, non-enveloped, positive-sense single-stranded RNA viruses. Together they form group of viruses that in humans cause diseases such as poliomyelitis, encephalitis, hand-foot-and-mouth ...
COVID-19 vaccine-induced adaptive immunity against SARS-CoV-2 variants
(Turun yliopisto, 2023-10-27)
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has necessitated the rapid development and deployment of vaccines worldwide. mRNA-based vaccines ...