Hae
Aineistot 1-10 / 48
Heavy metal exposure and estrous cyclicity in semi-captive Asian elephants (Elephas maximus)
(2022-09-08)
Background: Pollutants cause significant harm to ecosystems and organisms and have become a major concern. While some toxic substances are natural, like heavy metals, and others are anthropogenic like PCBs and microplastics, ...
Community dynamics in spatially structured experimental bacterial communities
(2022-06-30)
This master's thesis consists of seven separate parts. The first section is an introduction, during which I introduce basic concepts, for example, by explaining what a metacommunity and metapopulation are, what are the ...
Optimization of microbial DNA extraction in 96-format from fecal samples for Next Generation Sequencing
(2022-05-19)
Gut microbiota composition is often determined by using Next Generation Sequencing methods. The demand for rapid, efficient, and reliable microbial profiling is continuously increasing, thus making the optimization of ...
Escherichia coli ja Bacteroides vulgatus -bakteerien lipopolysakkaridien vaikutus tyypin 1 diabetekseen liittyviin autoimmuunimekanismeihin
(2022-05-19)
Tyypin 1 diabetes (T1D) on maailmanlaajuinen autoimmuunisairaus, jolle ei olla vielä keksitty parannus- tai ehkäisykeinoa. T1D vaatii jokapäiväistä verensokeriseurantaa sekä insuliinihoitoa ja voi johtaa hoitamattomana ...
The effect of macrophages on the hormone-releasing cells in mouse pituitary
(2022-05-12)
At the base of the brain is located the pituitary gland which secretes hormones to the bloodstream. Among other cells, the pituitary is resided by macrophages which take part in the immune system by phagocyting pathogens. ...
Effects of parental co-exposure to heat wave and copper on zebrafish (Danio rerio) offspring thermal tolerance
(2022-06-06)
Climate change driven intensification of heat waves and increased occurrence of toxins in the aquatic environments pose a challenge for ectotherms, such as fish. Changes in the environment not only can shape the individual ...
HOXB13-poistogeenisten eturauhassyöpäsolumallien luominen CRISPR-Cas9-menetelmällä
(2022-06-08)
Eturauhassyöpä on miesten yleisimpiin kuuluva syöpätyyppi. Sen kehittymiseen vaikuttavat muun muassa ikä ja etninen tausta. Myös perinnöllisyydellä on vaikutus syövän puhkeamiseen. Yksi tunnettu eturauhassyövälle altistava ...
Transgenerational effects of crude oil and heat shock on the mortality and oxygen consumption rate of Daphnia magna
(2022-07-26)
Baltic Sea is a compact area with heavy shipping activity, and since around 160 million metric tons of oil are transported annually, the risk of a major oil tanker spill is ever-present. Since climate change will raise sea ...
Vuosien 2009–2020 välillä esiintyneiden influenssavirus A/H1N1pdm09 -kantojen vertailu
(2021-11-19)
Influenssa A -virukset (IAV) aiheuttavat pelkästään Euroopassa miljoonia sairastapauksia ja kymmeniä tuhansia kuolemia vuosittain. Toisinaan influenssaepidemat laajenevat maailmanlaajuisiksi pandemioiksi, jolloin leviävä ...
Intestinal stem cell regulation by the hexosamine biosynthesis pathway in D. melanogaster
(2021-12-28)
The intestinal stem cells (ISC) of the D. melanogaster midgut, which is the functional analogue to mammalian small intestine, are highly responsive to changes in nutrition. ISC employ the hexosamine biosynthesis pathway ...