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Epidemiology of neurofibromatosis type 1 in Finland : incidence, mortality, pregnancies and congenital malformations
(Turun yliopisto, 2018-06-01)
Neurofibromatosis type 1 (NF1) is a dominantly inherited cancer syndrome, which is caused by mutations in the NF1 gene. Because of the high mutation rate of the gene, approximately half of the patients have a new mutation, ...
Classical pathway of the complement system in cutaneous squamous cell carcinoma
(Turun yliopisto, 2023-01-13)
Keratinocyte-derived cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer and it causes approximately 20% of all skin cancerrelated deaths. The incidence of cSCC is increasing worldwide. Usually ...
Risk factors and biomarkers for metastatic cutaneous squamous cell carcinoma
(Turun yliopisto, 2022-11-25)
The incidence of cutaneous squamous cell carcinoma (cSCC), the most common skin cancer with metastatic potential, continues to increase. Although proportion of cSCCs metastasize and cause mortality, sufficient means to ...
The role of complement factors D and I in cutaneous squamous cell carcinoma
(Turun yliopisto, 2023-09-30)
The most prevalent metastatic skin cancer is keratinocyte-derived cutaneous squamous cell carcinoma (cSCC), the incidence of which is growing worldwide. Although the most common mutations in cSCC have been identified, its ...