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A genome-wide association study of CYP1A2 activity using tizanidine and caffeine as probe drugs
(2022-01-13)
Cytochrome P450 (CYP) enzymes are the major drug metabolizing enzyme group. The highest level of CYPs is expressed in the liver, and the human cytochrome P450 (CYP) 1A2 is one of the major CYPs playing an important role ...