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Aineistot 171-180 / 247
Old acquaintances and new perspectives into testicular development and function
(Turun yliopisto, 2020-11-27)
Testicular development and function are complex processes that involve synchronization of the proliferation, apoptosis, and differentiation of specific somatic and germ cells to ensure lifelong fertility. Dysregulation of ...
Molecular imaging and immunotherapy in atherosclerotic cardiovascular disease
(Turun yliopisto, 2020-11-28)
Atherosclerotic cardiovascular disease (ASCVD) is a disorder that affects both heart and blood vessels. It is caused by atherosclerosis, a chronic, low-grade inflammatory disease, which is characterized by the accumulation ...
Lymphatic endothelial cells regulate traffic in lymph nodes
(Turun yliopisto, 2020-10-23)
Afferent lymphatic vessels transport leukocytes and soluble molecules from the periphery to lymph nodes. These vessels are lined with lymphatic endothelial cells (LEC), which are also present in lymph node sinuses. Lymph ...
Screening of novel therapeutic targets and risk alleles for cardiac disorders
(Turun yliopisto, 2020-11-27)
Ischemic heart disease is the leading cause of death globally, even though the prognosis of the disease has improved with advancing treatments. One particular phenomenon which could be treated more effectively is ...
Pathogenesis of LMNA-related dilated cardiomyopathy
(Turun yliopisto, 2022-03-04)
Dilated cardiomyopathy (DCM) is a progressive myocardial disease that leads to dilatation of cardiac ventricles, reduced contractile force, and a high risk of sudden cardiac death. The second most common gene mutated in ...
Ranteen alueen makroskooppinen anatomia – video-opetusmateriaali anatomian opiskeluun
(Turun yliopisto, 2017-02-22)
Tämän opinnäytetyön tarkoituksena oli luoda nykyaikaista ja suomenkielistä video-opetusmateriaalia anatomian opiskelua varten. Kohdeyleisöksi tarkennettiin toisen vuoden lääketieteen opiskelijoiden ...
Regulation of cell growth, death, and polarization by ERBB4
(Annales Universitatis Turkuensis D 991Turun yliopisto, 2011-11-25)
<b>Regulation of cell growth, death, and polarization by <i>ERBB4</i></b>
ErbB4 is a member of the epidermal growth factor receptor (EGFR, ErbB) family. The other members are EGFR, ErbB2 and ErbB3. ErbB receptors are ...
Biosynthesis of Yersinia enterocolitica serotype O:3 lipopolysaccharide outer core
(Annales Universitatis Turkuensis D 927Turun yliopisto, 2010-11-19)
Lipopolysacharide (LPS) present on the outer leaflet of Gram-negative bacteria is important for the adaptation of the bacteria to the environment. Structurally, LPS can be divided into three parts: lipid A, core and ...
Application of RNAi to silence tartrate-resistant acid phosphatase: unexpected effects on the monocyte-macrophage lineage
(Turun yliopisto, 2007-11-02)
<b>Tartraatti-resistentin happaman fosfataasin hiljentäminen RNAi menetelmällä: odottamaton vaikutus monosyytti-makrofagi linjan soluissa</b>
RNA interferenssi (RNAi) eli RNA:n hiljentyminen löydettiin ensimmäisenä ...
Dissecting the molecular mechanisms of breast cancer bone metastasis for therapeutic targeting
(Annales Universitatis Turkuensis D 1008Turun yliopisto, 2012-04-14)
Breast cancer that has metastasized to bone is currently an incurable disease, causing
significant morbidity and mortality. The aim of this thesis work was to elucidate
molecular mechanisms of bone metastasis and thereby ...