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Aineistot 21-30 / 38
The effects of prenatal corticosterone and thyroid hormone on great tit (Parus major) DNA methylation and gene expression
(2021-06-01)
Offspring phenotype is determined by genotype and environmental factors such as
maternal hormones during embryonic development. Avian eggs contain multiple
hormones of maternal origin. Differences in egg hormone ...
Luonnontieteiden ja matematiikan integraatio biologian alan oppimistehtävissä : Osmoosi-ilmiö oppimisen kohteena
(2023-04-28)
Peruskoulussa ja lukiossa opiskellaan oppiaineita, jotka perustuvat tieteenaloille, joissa tietoa luodaan tieteenalalle tyypillisin menetelmin ja käsittein. Oikean maailman ilmiöt eivät kuitenkaan noudata tieteenalojen ...
Db/db-hiirimalli aineenvaihduntasairauksien tutkimuksessa
(2023-05-18)
Lihavuus on yleistynyt maailmanlaajuiseksi epidemiaksi ja sen myötä myös monien aineenvaihduntasairauksien, kuten tyypin 2 diabeteksen, yleisyys on lisääntynyt. Näiden sairauksien tutkimukseen on käytetty erilaisia ihmisen ...
Kromosomin 12 trisomian vaikutus ihmisen pluripotentteihin kantasoluihin ja indusoidun kantasolulinjan luominen
(2022-12-02)
Pluripotenteilla kantasoluilla on kyky erilaistua jokaiseksi ihmiskehon solutyypiksi. Pluripotentteja alkion kantasoluja voidaan eristää blastokystivaiheen alkion sisäsolumassasta. Indusoituja pluripotentteja kantasoluja ...
Effects of CASP8 mutations on radiotherapy and inflammatory responses in cancer cells
(2023-05-29)
CASP8 mutations occur most commonly in head and neck squamous cell carcinoma (HNSCC), with a mutation frequency of 10,7 %. Alterations in this gene have been shown to impair the effects of radiotherapy in HNSCC patients ...
Community-level antimicrobial resistance in response to temporal gradients of antibiotic stress
(2023-05-18)
The development of antimicrobial resistance poses a global threat to human health. However, antimicrobial resistance has mainly been studied from a clinical perspective in single bacterial isolates. The purpose of this ...
Effects of the STRIP dietary intervention on blood cell transcriptome and activity of signaling pathways
(2023-05-25)
Atherosclerotic cardiovascular diseases (CVDs) are the largest group of diseases causing deaths. CVD risk may be reduced with following the dietary and other lifestyle recommendations. Diet can affect gene expression both ...
Stress-associated changes in the gut microbiome of Asian elephants
(2023-02-07)
Background: The intestinal tract of practically all animals is inhabited by a diverse microorganism referred to as gut microbiome. The importance of gut microbiome to its host is well known and an increasing number of ...
Genomic editing to elucidate the effects of PIM kinases on cancer cell signalling
(Turun yliopisto, 2023-03-31)
In humans, there are three PIM family genes, the two first of which were originally identified from mice as proviral integration sites for Moloney leukemia virus. They encode serine/threonine kinases that are aberrantly ...
Blood donor biobank suitability for identifying carriers with disease associated variants enriched in Finland
(2022-12-05)
Biobanks collect samples from donors for medical research. Blood Service Biobank consists of samples from healthy enough blood donors, and it is assumed to be useful source for population and health studies because of the ...