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Bidirectional relationship between health behavior and subjective well-being in adults
(Turun yliopisto, 2022-03-18)
Unhealthy behavior increases the unsustainable burden of chronic diseases on health care and changing health behavior is often personally challenging. The present thesis provides a new, positive perspective to investigating ...
Observations on the Pharmacokinetics and Pharmacodynamics of Dexmedetomidine. Clinical Studies on Healthy Volunteers and Intensive Care Patients
(Annales Universitatis Turkuensis D 1004Turun yliopisto, 2012-03-16)
Patients treated in intensive care units require sedation and analgesia. However,
sedative drugs also have potential adverse effects, and there is no single ideal sedativeanalgesic
drug for these patients.
Dexmedetomidine ...
Imaging Alzheimer’s Disease Beta-amyloid Pathology in Transgenic Mouse Models Using Positron Emission Tomography
(Annales Universitatis Turkuensis D 1294Turun yliopisto, 2017-06-16)
Accumulation of beta-amyloid (Aβ) in the brain is known to have an important role in the complex chain of pathological events leading to Alzheimer’s disease (AD). Based on current knowledge, Aβ is also seen as an interesting ...
Genetically Determined Hypometabolism in Alzheimer’s Disease and Midlife Risk Factors for Cognitive Impairment
(Annales Universitatis Turkuensis D 1011Turun yliopisto, 2012-06-06)
The role of genetic factors in the pathogenesis of Alzheimer’s disease (AD) is not completely
understood. In order to improve this understanding, the cerebral glucose metabolism of seven
monozygotic and nine dizygotic ...
Erectile dysfunction in cardiovascular risk population
(Annales Universitatis Turkuensis D 1202Turun yliopisto, 2015-11-06)
The inability to achieve and to maintain erection, erectile dysfunction, is a bothersome symptom of elderly men. Moreover, there is a high comorbidity between cardiovascular diseases and erectile ...
Early-Onset Hypertension – Clinical characteristics and relation to adverse outcomes
(Turun yliopisto, 2021-09-03)
ABSTRACT
Established hypertension is a well-known risk factor for cardiovascular disease and dementia. However, limited evidence exists on the relation between the age of hypertension onset and adverse events. The aim ...
Prediction of neurodevelopment and neuromotor trajectories in very preterm born children up to 11 years of age: PIPARI Study
(Annales Universitatis Turkuensis D 1226Turun yliopisto, 2016-05-20)
Very preterm birth is a risk for brain injury and abnormal neurodevelopment. While the incidence of cerebral palsy has decreased due to advances in perinatal and neonatal care, the rate of less severe neuromotor problems ...
Uncomplicated Acute Appendicitis – Studies on Diagnosis and Treatment Outcomes
(Turun yliopisto, 2021-08-20)
ABSTRACT
Appendectomy has been the indisputable treatment of acute appendicitis for over a century. Acute appendicitis has been evaluated to always progress to perforation. Current evidence suggests complicated and ...
Benzodiazepines and Cognitive Functioning in Older Adults. With Emphasis on Long-Term Use and Withdrawal
(Annales Universitatis Turkuensis D 1110Turun yliopisto, 2014-05-23)
Benzodiazepines (BZD) and benzodiazepine related drugs (RD) are the most commonly used psychotropics among the aged. The use of other psychotropics taken concomitantly with BZD/ RD or their cognitive effects with BZD/RD ...
Sick leave prescribing practices in Finland
(Annales Universitatis Turkuensis D 1132Turun yliopisto, 2014-11-21)
Background: Sick leave prescribing is a common task of doctors and being on sick leave results in notable economic consequences to society. However, there appears to be limited research into this field and the factors ...