Hae
Aineistot 321-330 / 578
Identification and characterization of new genes and pathways regulating spermatogonial cell fate
(Annales Universitatis Turkuensis D 1020Turun yliopisto, 2012-08-17)
Spermatogenesis, i.e sperm production in the seminiferous tubules of the testis, is a complex
process that takes over one month to complete. Life-long ability of sperm production ultimately
lies in a small population of ...
Adipose tissue in health and disease – implications to cardiovascular diseases
(2020-11-23)
Two major roles of adipose tissue are to function as a fat storage and an endocrine organ. Adipose tissue stores excess fat in adipocytes and releases when needed. Adipose tissue also secretes hormones, called adipokines, ...
Identification of novel regulators for tumor progression in breast cancer
(Annales Universitatis Turkuensis D 1037Turun yliopisto, 2012-11-09)
Breast cancer is the most frequent solid tumor among women and the leading
cause of cancer related death in women worldwide. The prognosis of breast
cancer patients is tightly correlated with the degree of spread beyond ...
Fibroblast Growth Factor 8 and its Receptors in The Growth and Angiogenesis of Experimental Breast Cancer . With Special Reference to Thrombospondin-1 as a Novel Target Gene for FGF-8
(Annales Universitatis Turkuensis D 949Turun yliopisto, 2011-02-25)
The growth of breast cancer is regulated by hormones and growth factors. Recently, aberrant fibroblast growth factor (FGF) signalling has been strongly implicated in promoting the progression of breast cancer and is thought ...
High-Throughput Screening for Novel Prostate Cancer Drug Targets –Getting Personal
(Annales Universitatis Turkuensis D 994Turun yliopisto, 2011-11-25)
Prostate cancers form a heterogeneous group of diseases and there is a need for novel biomarkers, and for more efficient and targeted methods of treatment. In this thesis, the potential of microarray data, RNA interference ...
Filopodia and stromal extracellular matrix as regulators of cancer cell invasion and growth
(Annales Universitatis Turkuensis D 1225Turun yliopisto, 2016-04-22)
Bidirectional exchange of information between the cancer cells and their environment is essential for cancer to evolve. Cancer cells lose the ability to regulate their growth, gain the ability to detach ...
Molecular patterns behind immunological and metabolic alterations in lysinuric protein intolerance
(Annales Universitatis Turkuensis D 1220Turun yliopisto, 2016-03-05)
Lysinuric protein intolerance (LPI) is a recessively inherited disorder characterised by reduced plasma and increased urinary levels of cationic amino acids (CAAs), protein malnutrition, growth failure and hyperlipidemia. ...
Dissecting New Molecular Mechanisms in Thyroid Diseases Using Genetically Modified Mouse Models
(Annales Universitatis Turkuensis D 1257Turun yliopisto, 2016-10-28)
The thyroid gland secretes thyroid hormones (THs) under regulation of thyroid stimulation hormone (TSH) and its receptor (TSHR). THs play a pivotal role in development, growth and metabolism.
An increased secretion of ...
Bioimage informatics in STED super-resolution microscopy
(Annales Universitatis Turkuensis D 1219Turun yliopisto, 2016-03-04)
Optical microscopy is living its renaissance. The diffraction limit, although still physically true, plays a minor role in the achievable resolution in far-field fluorescence microscopy. Super-resolution ...
Synnynnäinen hypotyreoosi
(Turun yliopisto, 2017-03-14)