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Aineistot 431-440 / 581
A Farewell to Flat Biology. Three-dimensional Cell Culture Models in Cancer Drug Target Identification and Validation
(Annales Universitatis Turkuensis D 1028Turun yliopisto, 2012-09-14)
Cells of epithelial origin, e.g. from breast and prostate cancers, effectively differentiate into complex multicellular structures when cultured in three-dimensions (3D) instead of conventional two-dimensional (2D) adherent ...
The role of PLVAP protein in endothelial cells of liver
(2021-02-09)
In endothelial cells (EC) PLVAP protein forms permeability regulating structures known as diaphragms. In some previous studies it has been stated that PLVAP does not exist in adult liver ECs, because diaphragms of liver ...
Unraveling significance of receptor-ligand interaction on Jagged1 mobility, filopodia and ligand clustering in the Notch signaling pathway
(2019-08-02)
The Notch signaling pathway plays a crucial role in many diseases. It has been proven that the Notch pathway is involved with several human cancers, including T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma. It ...
Rintasyövän uusintaleikkaukset Turun yliopistollisessa keskussairaalassa vuosina 2008-2018
(2021-03-25)
Rintasyövän ensisijainen leikkaustapa on rinnan osapoisto, mikäli vasta-aiheita ei ole. Joskus leikkauksen tervekudosmarginaalit voivat jäädä riittämättömiksi, ja tällöin joudutaan tekemään uusintaleikkaus. Tämän tutkimuksen ...
Diet and physical activity of primary school aged children and their association with child's overweight and obesity
(2021-03-26)
Abstract
Background: Overweight and obesity are common problems in children. it is significantly affected by lifestyles such as nutrition and physical activity. parental obesity as well as activity and family socioeconomic ...
IHOHISTOLOGIAN ITSEOPISKELUN TUKEMINEN PELILLISTÄMISEN AVULLA
(2021-03-30)
Näiden syventävien opintojen tarkoituksena oli tuottaa ihohistologiaa käsittelevää verkkopohjaista lisäoppimateriaalia lääketieteen, hammaslääketieteen ja biolääketieteen toisen vuoden opiskelijoille Patologia II -kurssille. ...
Self-reported healthy dietary behavior relates to parental attitudes on child feeding, health and diet quality.
(2021-03-22)
Parents influence their children´s diet greatly as seen in earlier research. In addition, it
is known that both diet and obesity in childhood tend to persist and therefore affect to
the risk of several chronic lifestyle ...
The effects of transgenic melanocortin overexpression in atherosclerotic mice
(Turun yliopisto, 2016-12-14)
Atherosclerosis is a chronic inflammatory disease of the arteries and a common cause of death worldwide. The disease is initiated by endothelial dysfunction that allows the transport of leukocytes and ...
Identification of RasGEFs counteracting neuronal SynGAP1 function
(2021-05-11)
SynGAP syndrome refers to an under-diagnosed group of diseases caused by the mutation of the SynGAP1 gene encoding the predominant synaptic protein SynGAP1. SynGAP1 is a Ras GTPase activating protein that is a major regulator ...
Establishment of 3D co-culture model of mesenchymal stem cells and mononuclear cells for studying vasculogenesis/angiogenesis, and the magnetic isolation of endothelial progenitor cells from mononuclear cells
(2019-02-05)
Bone tissue engineering that stimulates bone formation has improved normal fracture healing, but its true clinical impact is still lacking. One of the biggest problems with bone tissue engineered grafts is an inadequate ...